51207-43-3

Basic information

• Product Name: methyl 4-{[(4-methylphenyl)sulfonyl]oxy}benzoate
• Synonyms: methyl 4-{[(4-methylphenyl)sulfonyl]oxy}benzoate
• CAS NO: 51207-43-3
• Molecular Formula: C₁₅H₁₄O₅S
• Molecular Weight: 306.33366
• Mol File: 51207-43-3.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 4-{[(4-methylphenyl)sulfonyl]oxy}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-{[(4-methylphenyl)sulfonyl]oxy}benzoate(51207-43-3)
• EPA Substance Registry System: methyl 4-{[(4-methylphenyl)sulfonyl]oxy}benzoate(51207-43-3)

Safety Data

• Hazardous Substances Data: 51207-43-3(Hazardous Substances Data)

Upstream product

• 99-76-3 methyl 4-hydroxylbenzoate 
• 98-59-9 p-toluenesulfonyl chloride 
• 67-56-1 methanol 
• 51804-15-0 4-carboxyphenyl 4-methylbenzenesulfonate 

Downstream Products

• 792-74-5 4,4'-biphenyldicarboxylic acid dimethyl ester 
• 720-75-2 methyl 4-phenylbenzoate 
• 20651-69-8 methyl 4-(n-butyl)benzoate 
• 38409-63-1 4-hexylbenzoic acid methyl ester 
• 99-75-2 4-methyl-benzoic acid methyl ester 
• 53355-25-2 methyl 4-(2-furanyl)benzoate 
• 443296-78-4 4-{[(4-methylphenyl)sulfonyl]oxy}benzoic acid hydrazide 
• 121866-32-8 4-hept-1-ynyl-benzoic acid methyl ester 
• 171364-80-0 methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 51804-15-0 4-carboxyphenyl 4-methylbenzenesulfonate 
• 619-44-3 methyl 4-iodobenzoate 
• 23676-05-3 4-morpholin-4-yl-benzoic acid methyl ester 
• 67852-98-6 methyl 4-(tert-butylcarbamoyl)benzoate 
• 38337-00-7 methyl 4-(benzenesulfonyl)benzoate 

Relevant articles and documents

Nickel-catalyzed methylation of aryl halides/tosylates with methyl tosylate

This work describes the cross-electrophile methylation of aryl bromides and aryl tosylates with methyl tosylate. The mild reaction conditions allow effective methylation of a wide set of heteroaryl electrophiles and dimethylation of dibromoarenes.

Aminocarbonylation of Aryl Tosylates to Carboxamides

The palladium - catalyzed aminocarbonylation of aryl tosylates with amines is reported. Suitable conditions were identified by high throughput reaction screening and then further optimized. The substrate scope of the reaction with respect to the aryl tosylate component and the amine component are reported. Competitive aminolysis of the aryl tosylates to afford the amine toluenesulfonamides and the phenol was not observed.

Zn(OTf)2-promoted chemoselective esterification of hydroxyl group bearing carboxylic acids

Selective esterification of aliphatic and aromatic carboxylic acids with various alcohols is studied using triphenylphosphine, I2, and a catalytic amount of Zn(OTf)2. Use of this catalyst allows the formation of esters at a faster rate with good to excellent yield by activating the in situ generated acyloxyphosphonium ion intermediate. During the esterification process, both their aromatic and aliphatic hydroxyl groups are fully preserved from transesterification. The results show that the bulkiness and the reactivity of this doubly activated intermediate III control the selectivity and the rate of the reaction, respectively. The method is also useful for direct amidation reactions.