512182-38-6

Basic information

• Product Name: 1-(p-methoxybenzyl)-5-phenyl-1H-tetrazole
• Synonyms: 1-(p-methoxybenzyl)-5-phenyl-1H-tetrazole
• CAS NO: 512182-38-6
• Molecular Weight: 266.302
• Mol File: 512182-38-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(p-methoxybenzyl)-5-phenyl-1H-tetrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(p-methoxybenzyl)-5-phenyl-1H-tetrazole(512182-38-6)
• EPA Substance Registry System: 1-(p-methoxybenzyl)-5-phenyl-1H-tetrazole(512182-38-6)

Safety Data

• Hazardous Substances Data: 512182-38-6(Hazardous Substances Data)

Usage

Type of compound

Tetrazole derivative

Substituents

a. p-methoxybenzyl group
b. Phenyl group

Structure

The tetrazole ring is attached to a benzyl group with a methoxy substitution on the para position, and a phenyl group is attached to the tetrazole ring.

Pharmaceuticals

Due to its tetrazole structure, it has been studied for antihypertensive, diuretic, and vasodilator properties.

Corrosion inhibitors

Tetrazoles have been investigated for their potential use as corrosion inhibitors.

Propellants and explosives

Tetrazoles have been studied as additives in propellants and explosives.

Chemical properties

The presence of the methoxybenzyl and phenyl groups may impart specific chemical properties, such as reactivity, stability, and solubility, that make it useful for various industrial and research applications.

Biological properties

The specific substitution pattern and functional groups in the compound may influence its interaction with biological targets, potentially leading to novel therapeutic or diagnostic applications.

Upstream product

• 18039-42-4 5-Phenyl-1H-tetrazole 
• 824-94-2 p-methoxybenzyl chloride 
• 2393-23-9 4-methoxy-benzylamine 
• 98-88-4 benzoyl chloride 
• 41882-10-4 N-(4-methoxybenzyl)benzamide 

Downstream Products

• 1307853-51-5 2-butyl-4-chloro-1-({2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]-biphenyl-4-yl}-methyl)imidazole-5-carbaldehyde 
• 1307853-52-6 2-butyl-4-chloro-1-({2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]-biphenyl-4-yl}-methyl)imidazole-5-methanol 
• 1307853-38-8 {2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]biphenyl-4-yl}-methanol 
• 1307853-40-2 5-[4'-(bromomethyl)biphenyl-2-yl]-1-(p-methoxybenzyl)-1H-tetrazole 
• 114798-36-6 2-n-Butyl-4-chloro-1-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-imidazole-5-carboxaldehyde 
• 114798-26-4 lorsartan 
• 1301606-98-3 {2'-{1-(p-methoxybenzyl)-1H-tetrazol-5-yl}biphenyl-4-yl}methyl acetate 
• 1307853-45-7 1-(4-methoxybenzyl)-5-(4'-methylbiphenyl-2-yl)tetrazole 
• 145040-37-5 candesartan cilexetil 
• 676129-93-4 (S)-3-methyl-2-((2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl)-amino)-butyric acid benzyl ester 
• 1307853-55-9 benzyl N-({2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]biphenyl-4-yl}methyl)-L-valinate 
• 1307853-69-5 methyl 2-(N-tert-butoxycarbonyl-N-{(2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]biphenyl-4-yl)methyl}amino)-3-nitrobenzoate 
• 1307853-71-9 methyl 2-[({2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]biphenyl-4-yl}methyl)amino]-3-nitrobenzoate 
• 1307853-72-0 methyl 2-[({2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]biphenyl-4-yl}methyl)amino]-3-aminobenzoate 

Relevant articles and documents

PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE

The invention provides a production method of a biaryltetrazole derivative useful as an intermediate for an angiotensin II receptor antagonist. The method comprises reacting an aryltetrazole derivative with a benzene derivative, deprotecting or reducing the resulting compound, and halogenating the deprotected or reduced compound

REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS

A pharmaceutical composition for the prophylaxis and/or treatment of diseases induced, exacerbated or reignited by stressors comprising the compound of formula (I) wherein all symbols have the same meanings as described in the specification, etc. as an active ingredient.