676129-93-4

Usage

Chemical Properties

Brown Solid

Upstream product

• 98-88-4 benzoyl chloride 
• 21388-92-1 4-bromobenzyl acetate 
• 873-75-6 4-bromobenzenemethanol 
• 18039-42-4 5-Phenyl-1H-tetrazole 
• 512182-38-6 1-(p-methoxybenzyl)-5-phenyl-1H-tetrazole 
• 41882-10-4 N-(4-methoxybenzyl)benzamide 
• 1307853-55-9 benzyl N-({2'-[1-(p-methoxybenzyl)-1H-tetrazol-5-yl]biphenyl-4-yl}methyl)-L-valinate 
• 1301606-98-3 {2'-{1-(p-methoxybenzyl)-1H-tetrazol-5-yl}biphenyl-4-yl}methyl acetate 
• 676130-02-2 5-(2-bromophenyl)-2-(tetrahydropyran-2-yl)-2H-tetrazole 
• 676130-06-6 5-(4'-diethoxymethyl-biphenyl-2-yl)-2-(tetrahydro-pyran-2-yl)-2H-tetrazole 
• 73096-42-1 5-(2-bromophenyl)-1H-tetrazole 
• 34421-94-8 4-bromobenzaldehyde diethyl acetal 
• 21760-98-5 L-valine benzyl ester 
• 16652-76-9 L-valine benzyl ester p-toluenesulfonate salt 

Downstream Products

• 137863-20-8 (S)-N-(1-benzyloxycarbonyl-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amine 
• 137862-53-4 N-pentanoyl-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]-methyl]-(L)-valine 

Relevant academic research and scientific papers

PROCESS FOR PRODUCTION OF BIPHENYL DERIVATIVE

The invention provides a production method of a biaryltetrazole derivative useful as an intermediate for an angiotensin II receptor antagonist. The method comprises reacting an aryltetrazole derivative with a benzene derivative, deprotecting or reducing the resulting compound, and halogenating the deprotected or reduced compound

PROCESS FOR THE MANUFACTURE OF VALSARTAN

The present invention relates to a process for the manufacture of Valsartan, an angiotensin receptor blocker (ARB; also called angiotension II receptor antagonist or AT1 receptor antagonist) and salts thereof, to novel intermediates and process steps.