512779-26-9Relevant academic research and scientific papers
Alternative synthetic routes to 2′,3′-didehydro-2′,3′-dideoxy-5-hydroxymethyluridine
Chung, Raymond,Anderson, Karen S.
, p. 8361 - 8363 (2007/10/03)
Alternative syntheses for the nucleoside analogue 2′,3′-didehydro-2′,3′-dideoxy-5-hydroxymethyluridine starting from 5-methyluridine and uridine are described.
Efficient synthesis of 5-hydroxymethyl pyrimidines and their nucleosides using microwave irradiation
Abdel-Rahman, Adel A.-H.,El Ashry, El Sayed H.
, p. 2043 - 2044 (2007/10/03)
Hydroxymethylation of uracil (1), cytosine (3), 5-hydroxymethyl-2′,3′-O-isopropylideneuridine (5), 5′-O-tert-butyldiphenylsilyl-2′,3′-O-isopropylideneuridine (7), 2′,3′-O-isopropylidenecytidine (9) and 2′,3′-O-isopropylidene-5′-O-tritylcytidine (11) was efficiently carried out with paraformaldehyde in alkaline medium under microwave irradiation in very high yield.
