5138-90-9

Basic information

• Product Name: 4-CHLOROBENZENESULFONIC ACID SODIUM SALT
• Synonyms: 4-chloro-benzenesulfonicacisodiumsalt;p-chlorbenzensulfonansodny;p-chlorobenzenesulfonic;p-chloro-benzenesulfonicacisodiumsalt;sodiumpara-chlorobenzosulphate;P-CHLOROBENZENESULFONIC ACID SODIUM SALT;SODIUM-P-CHLOROBENZENESULFONATE;SODIUM 4-CHLOROBENZENESULFONATE
• CAS NO: 5138-90-9
• Molecular Formula: C₆H₄ClO₃S*Na
• Molecular Weight: 214.6
• EINECS: 225-900-2
• Mol File: 5138-90-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 258.6°Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.551g/cm³
• Vapor Pressure: 0.00696mmHg at 25°C
• Water Solubility: almost transparency
• CAS DataBase Reference: 4-CHLOROBENZENESULFONIC ACID SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLOROBENZENESULFONIC ACID SODIUM SALT(5138-90-9)
• EPA Substance Registry System: 4-CHLOROBENZENESULFONIC ACID SODIUM SALT(5138-90-9)

Safety Data

• Safety Statements: 22-24/25
• RTECS: DB5620000
• Hazardous Substances Data: 5138-90-9(Hazardous Substances Data)

Usage

Purification Methods

Crystallise it twice from MeOH and dry it under vacuum. [Beilstein 11 IV 107.]

InChI:InChI=1/C6H5ClO3S.Na/c7-5-1-3-6(4-2-5)11(8,9)10;/h1-4H,(H,8,9,10);/q;+1/p-1

Upstream product

• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 81292-95-7 4-Chlor-1-benzolsulfonsaeure-trimethylsilylester 
• 110143-20-9 α-(p-chlorobenzenesulfonyloxy)acetophenone 
• 38950-28-6 sodium 3,4-dichlorobenzenesulfonate 
• 31081-11-5 4-Chloro-benzenesulfonic acid toluene-4-sulfonylmethyl ester 

Downstream Products

• 110143-20-9 α-(p-chlorobenzenesulfonyloxy)acetophenone 
• 38950-28-6 sodium 3,4-dichlorobenzenesulfonate 
• 74-11-3 para-chlorobenzoic acid 
• 74758-55-7 4-hydroxymethylbiphenyl-4'-sulphonic acid 
• 98-60-2 4-chlorobenzenesulfonyl chloride 
• 15925-05-0 1.4-Phenylenbis 
• 92150-69-1 1-chloro-4-((phenylethynyl)sulfonyl)benzene 
• 1582221-62-2 ethyl 5-(4-chlorophenyl)-2-phenyloxazole-4-carboxylate 
• 32228-16-3 (Z)-(styryl)(4-chloro-phenyl)sulfide 
• 32228-21-0 (E)-(styryl)(4-chloro-phenyl)sulfide 
• 4899-13-2 (E)-2-(2-((4-chlorophenyl)thio)vinyl)thiophene 
• 21081-94-7 diphenylthiophosphinic acid-S-4-chlorophenyl ester 
• 59985-46-5 (4-chlorophenyl)(octyl)sulfane 

Relevant articles and documents

Synthesis of 3-chloro-Δ3-cephem-4-carboxylate by addition/cyclization of allenecarboxylate. Copper(II)-promoted aerobic oxidation of arenesulfinic acids

The selective transformation of allenecarboxylate derived from penicillin into 3-chloro-Δ3-cephem-4-carboxylate was successfully achieved by an addition/cyclization reaction with chloride salts in aerobic media containing a copper(II) catalyst, in which copper(II)-catalyzed aerobic oxidation of in situ generated benzenesulfinate ion into less nucleophilic sulfonate ion prior to the nucleophilic addition of the former ion to the allenecarboxylate would completely eliminate the formation of undesired 3-phenylsulfonyl-Δ3-cephem-4-carboxylate. Under similar aerobic conditions, arenesulfinates salts and arenesulfinic acids were smoothly oxidized to the corresponding sulfonate salts and sulfonic acids, respectively.

Reaction of rifamycins with sodium sulfinates

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Micellar Effects on the Reaction of (Arylsulfonyl)alkyl Arenesulfonates with Hydroxide Ion. Microenvironmental and Substituent Effects in the Stern Layer of Cationic Micelles

The reaction of the sulfonates p-XC6H4SO2CH(R)OSO2C6H4Y-p 1a-g with hydroxide ion (involving nucleophilic attack at sulfonate sulfur) is accelerated (7-25 times) in the presence of CTAB micelles (32.1 deg C).The kinetic data are analyzed in detail by using the pseudophase ion-exchange (PPIE) model, taking into account partitioning of the reactants between the micellar and aqueous pseudophases and competition between hydroxide ions and detergent counterions for binding to the micelles.Binding constants obtained from the kinetic analysis are compared with those from ultrafiltration experiments.Generally, the PPIE model reproduces the experimental rate constants quite well, except at low detergent concentration (around the cmc).The second-order rate constants for reaction in the micellar pseudophase are 4-12 times smaller than those for reaction in bulk water.Therefore the observed catalysis is purely the result of the high local concentration of both reactants in the micellar pseudophase.The substituent effects for the reaction in the micelles reveal an increased susceptibility for variation of Y.No evidence for orientational effects was found.It is shown that the binding of the sulfonates with the micelles is mainly determined by the presence of the aryl groups.Based on a comparison with kinetic solvent effects on the reaction in 1,4-dioxane-water, it is suggested that the rates in the micellar pseudophase reflect a decrease in micropolarity at the binding sites of the substrate molecules.