51639-58-8

Usage

Uses

Given the limited information available, it is not possible to provide a detailed list of applications for CHEMBRDG-BB 9070750. However, it can be inferred that this chemical may be used in various scientific, industrial, or academic applications, depending on its properties and characteristics. Further information would be required to determine its specific uses in different industries.

InChI:InChI=1/C8H12N2/c1-2-9-7-8-5-3-4-6-10-8/h3-6,9H,2,7H2,1H3

Upstream product

• 55401-97-3 2-(Bromomethyl)pyridine 
• 75-04-7 ethylamine 
• 1121-60-4 pyridine-2-carbaldehyde 

Downstream Products

• 680591-11-1 N-ethyl-N-pyridin-2-ylmethyl-2-p-tolylamino-acetamide 
• 952195-42-5 2-[(6-Chloro-3-methyl-benzo[d]isothiazol-5-yl)-(3,4-dimethoxy-benzenesulfonyl)-amino]-N-ethyl-N-pyridin-2-ylmethyl-acetamide 
• 209416-28-4 N-(2'-pyridylmethyl)-N-ethyl-4-(2,4,6-trimethyphenyl)-1phthalazinamine 

Relevant academic research and scientific papers

First Nondiscriminating Translocator Protein Ligands Produced from a Carbazole Scaffold

Development of neuroinflammation agents targeting the translocator protein (TSPO) has been hindered by a common single nucleotide polymorphism (A147T) at which TSPO ligands commonly lose affinity. To this end, carbazole acetamide scaffolds were synthesized and structure activity relationships elaborated to explore the requirements for high-affinity binding to both TSPO wild type (WT) and the polymorphic TSPO A147T. This study reports high binding affinity and nondiscriminating TSPO ligands.

2-ARYL IMIDAZO[1,2-A]PYRIDINE-3-ACETAMIDE DERIVATIVES, PREPARATION METHODS AND USE THEREOF

Disclosed are 2-arylimidazo[1,2-a]pyridine-3-acetamide derivatives represented by formula I, their tautomer, racemate or optical isomer, their pharmaceutically acceptable salt, or their solvates, wherein R1, R2, R3 and R4 are defined as in the specification. Preparation methods of said compounds and use of said compounds in treating and/or preventing central nervous system disease associated with TSPO functional disorder

2-Aryl Imidazo[1,2-a]Pyridine-3-Acetamide Derivatives, Preparation Methods and Uses Thereof

Disclosed are 2-arylimidazo[1,2-a]pyridine-3-acetamide derivatives represented by formula I, their tautomer, racemate or optical isomer, their pharmaceutically acceptable salt, or their solvates, wherein R1, R2, R3 and R4 are defined as in the specification. Preparation methods of said compounds and use of said compounds in treating and/or preventing central nervous system disease associated with TSPO functional disorder

NOVEL SULFONAMIDE COMPOUNDS

The invention relates to novel sulfonamide compounds and their use as orexin receptor antagonists.

SORDARIN DERIVATIVES FOR PREVENTING OR TREATING INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS

This invention relates to a new sordarin derivative or a pharmaceutically acceptable salt thereof, which has antimicrobial activities (especially, antifungal activities), to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases in a human being or an animal.

NOVEL SULFONAMIDE COMPOUNDS

The invention relates to sulfonamide compounds of formula (I), where A, B, R3 and R4 are as defined in the claims, and their use as orexin receptor antagonists in the prevention and treatment of eating and drinking disorders, all types of sleep disorders, all kinds of cognitive dysfunctions in the healthy population and psychiatric and neurologic disorders. Formula (I).

SULFONYLAMINO-ACETIC ACID DERIVATIVES

The invention relates to novel sulfonylamino-acetic acid derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of such compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as orexin receptor antagonists.