51673-59-7

Basic information

• Product Name: 1-(2-Nitrophenyl)-1,2-ethanediol
• Synonyms: o-Nitrostyrene glycol;2-nitrophenyl glycol;1,2-Ethanediol, 1-(2-nitrophenyl)-;1-(2-Nitrophenyl)-1,2-ethanediol 98%;2-NITROSTYRENE GLYCOL;1-(2-NITROPHENYL)-1,2-ETHANEDIOL
• CAS NO: 51673-59-7
• Molecular Formula: C₈H₉NO₄
• Molecular Weight: 183.16
• EINECS: 1.41 g/cm³
• Mol File: 51673-59-7.mol
• Article Data: 9

Chemical Properties

• Melting Point: 96-98 °C(lit.)
• Boiling Point: 398.7 °C at 760 mmHg
• Flash Point: 180.5 °C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 4.51E-07mmHg at 25°C
• Refractive Index: 1.616
• PKA: 13.02±0.20(Predicted)
• CAS DataBase Reference: 1-(2-Nitrophenyl)-1,2-ethanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Nitrophenyl)-1,2-ethanediol(51673-59-7)
• EPA Substance Registry System: 1-(2-Nitrophenyl)-1,2-ethanediol(51673-59-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 51673-59-7(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Canadian Journal of Chemistry, 61, p. 400, 1983 DOI: 10.1139/v83-072

InChI:InChI=1/C8H9NO4/c10-5-8(11)6-3-1-2-4-7(6)9(12)13/h1-4,8,10-11H,5H2

Upstream product

• 579-71-5 2-nitrostyrene 
• 141-78-6 ethyl acetate 
• 88057-15-2 2-bromo-1-(2-nitro-phenyl)-ethanol 
• 6851-99-6 2-bromo-1-(2-nitrophenyl)ethanone 
• 552-89-6 2-nitro-benzaldehyde 
• 577-59-3 2-acetylnitrobenzene 
• 6388-74-5 p-Nitrophenyloxirane 

Downstream Products

• 51673-56-4 Acetic acid (3S,8S,10R,13S,14S,17S)-10,13-dimethyl-17-[2-methyl-4-(2-nitro-phenyl)-[1,3]dioxolan-2-yl]-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester 
• 51673-57-5 C₂₉H₃₇NO₆ 
• 51673-53-1 2-(2-Nitro-phenyl)-1,4-dioxa-spiro[4.5]decane 
• 62635-29-4 2,-dimethyl-4-(2-nitrophenyl)-1,3-dioxolane 
• 552-89-6 2-nitro-benzaldehyde 
• 51673-10-0 2-(4-Nitro-phenyl)-4-(2-nitro-phenyl)-[1,3]dioxolane 
• 203385-96-0 2-{2-[2-Amino-2-(2-nitro-phenyl)-ethoxy]-ethoxy}-1-(2-nitro-phenyl)-ethylamine 
• 203385-94-8 C₁₈H₁₈BrClN₂O₆ 
• 203385-93-7 2-[2-Chloro-2-(2-nitro-phenyl)-ethoxy]-ethanol 

Relevant articles and documents

Photoregulation of Gene Expression with Amantadine-Modified Caged siRNAs through Host–Guest Interactions

RNA interference is an essential and powerful tool for targeting and verifying specific gene functions. Conditional control of small interfering RNA (siRNA) activity, especially using light activation, is a potential method for regulating target gene expr

Photochemical regulation of gene expression using caged siRNAs with single terminal Vitamin E modification

Caged siRNAs with a single photolabile linker and/or vitamin E (vitE) modification at the 5′ terminal were rationally designed and synthesized. These virtually inactive caged siRNAs were successfully used to photoregulate both firefly luciferase and GFP g

Photocleavable circular oligonucleotides

The photocleavable cyclic oligonucleotide according to the invention is the one that possesses a base sequence having the hybridization ability toward DNA or RNA to targeted, and is further provided with the structure cyclized by a photocleavable group. Accordingly, the photocleavable cyclic oligonucleotide according to the invention, after having been introduced in vivo, is hardly susceptible to the nuclease decomposition reaction owing to its cyclic structure and thus it is capable of diffusing toward the predetermined sites in vivo with sufficient time. Moreover, by being irradiated with the light at an appropriate wavelength after a predetermined period of time, the photocleavable group as described above is cleaved photochemically, thus cutting the predetermined bond. This permits the oligonucleotide that was cyclic to be a linear oligonucleotide which expresses the function of an antisense oligonucleotide.