5176-82-9

Basic information

• Product Name: N,N'-dimethylparabanic acid
• Synonyms: N,N'-dimethylparabanic acid;1,3-Dimethyl-2,4,5-trioxoim;1,3-dimethylimidazolidine-2,4,5-trione;Cholestrophane;Oxalydimethylurea
• CAS NO: 5176-82-9
• Molecular Formula: C₅H₆N₂O₃
• Molecular Weight: 142.11274
• Mol File: 5176-82-9.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 276°Cat760mmHg
• Flash Point: 133.6°C
• Appearance: /
• Density: 1.416g/cm³
• Vapor Pressure: 0.00493mmHg at 25°C
• Refractive Index: 1.525
• CAS DataBase Reference: N,N'-dimethylparabanic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-dimethylparabanic acid(5176-82-9)
• EPA Substance Registry System: N,N'-dimethylparabanic acid(5176-82-9)

Safety Data

• Hazardous Substances Data: 5176-82-9(Hazardous Substances Data)

Usage

Uses

Chronic exposure to 1,3-Dimethylparabanic Acid can cause inhibition of growth population on rotifers while algae seems to be unaffected. Furthermore, 1,3-Dimethylparabanic Acid is a derivative of Caffeine (C080100). Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses.A study at Johns Hopkins U

InChI:InChI=1/C5H6N2O3/c1-6-3(8)4(9)7(2)5(6)10/h1-2H3

Upstream product

• 21035-65-4 1,3-Dimethyl-2-thioxoimidazolidin-4,5-dion 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 874-14-6 1,3-dimethyluracil 
• 67-56-1 methanol 
• 944-73-0 1,3-dimethyluric acid 
• 20041-90-1 caffeidine 
• 60-29-7 diethyl ether 
• 67-66-3 chloroform 
• 7697-37-2 nitric acid 
• 7647-01-0 hydrogenchloride 
• 5415-44-1 1,3,7-trimethyluric acid 
• 7732-18-5 water 
• 58-08-2 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione 
• 7782-50-5 chlorine 

Downstream Products

• 119695-61-3 N,N'-dimethyl-5-hydroxy-5-(3-hydroxy-1,1-diphenylpropyl)hydantoin 
• 119695-62-4 N,N'-dimethyl-5-hydroxy-5-(2-methoxy-1,1-diphenylethyl)hydantoin 
• 119695-64-6 N,N'-dimethyl-5-hydroxy-5-(3-hydroxy-1,1-diphenylbutyl)hydantoin 
• 119695-55-5 spiro 
• 119846-69-4 spiro 
• 98619-36-4 N,N'-dimethyl-5-hydroxy-5-cyclohexylhydantoin 
• 119695-59-9 spiro 
• 64732-10-1 5-hydroxy-1,3-dimethylimidazolidine-2,4-dione 
• 119695-73-7 N,N'-dimethyl-5-hydroxy-5-(4-cyclohexyl-2-butenyl)hydantoin 
• 119695-74-8 N,N'-dimethyl-5-hydroxy-5-(2-cyclohexyl-1-vinylethyl)hydantoin 
• 98619-34-2 N,N'-dimethyl-5-hydroxy-5-benzylhydantoin 
• 119695-72-6 (E)-N,N'-dimethyl-5-hydroxy-5-(5-phenyl-2-pentenyl)hydantoin 
• 119695-67-9 N,N'-dimethyl-5-hydroxy-5-(3-hydroxy-3-methyl-1,1-diphenylbutyl)hydantoin 
• 119695-68-0 N,N'-dimethyl-5-hydroxy-5-(1,1,3-triphenylpropyl)hydantoin 

Relevant articles and documents

Study of the methylation reaction of 2,4-dinitroimidazole and potassium 2,4,5-trinitroimidazol-1-ide with dimethyl sulfate

[Figure not available: see fulltext.] The methylation of 2,4-dinitroimidazole and potassium salt of 2,4,5-trinitroimidazole with dimethyl sulfate was reinvestigated. When the reaction system contained a weak base, the reaction products were 1-methyl-2,4-dinitroimidazole and 1-methyl-2,4,5-trinitroimidazole, respectively. However, in the absence of a base in the reaction system, the products contained oxidation byproducts 1-methylimidazolidine-2,4,5-trione, 1,3-dimethylimidazolidine-2,4,5-trione and recovered starting materials. All products were characterized using FT-IR, NMR, and elemental analysis. The structure of 1-methylimidazolidine-2,4,5-trione and 1,3-dimethylimidazolidine-2,4,5-trione were further confirmed by single crystal X-ray diffraction.

5,5′-bipyridyl-2,4,6,2′,4′,6′-hexaone derivatives (hydurilic acids): Syntheses, mechanism of C-C-Bond formation and properties of the dimeric barbituric acid derivatives

A series of hydurilic acid derivatives (5,5′-bipyrimidinyl-2,4,6,2′,4′,6′-hexaones) including several new derivatives was synthesized from 5,6-diaminouracils. Mechanisms for their formation are proposed and discussed. Furthermore, a new method for the preparation of pyrimidine-2,4,5,6-tetraone-5-oxime derivatives (violuric acids) was found starting from 5-amino-6-nitrosouracils.

Oxidation of nucleic acid related compounds by the peroxodisulfate ion

The treatment of nucleic acid bases, nucleosides, and nucleotides with peroxodisulfate ion in a phosphate buffer solution at pH 7.0 or water at 70-75°C was investigated. The reaction of thymine and 5-methylcytosine nucleosides and nucleotides resulted in the oxidation of the 5-methyl groups. The oxidation products from 1,3-dimethyluracils and the time-course of the reaction of uracils led to two plausible reaction mechanisms for the oxidation of uracils.