51769-82-5

Upstream product

• 108-24-7 acetic anhydride 
• 619-80-7 4-nitrobenzamide 
• 73823-16-2 N-[1-Dimethylamino-eth-(E)-ylidene]-4-nitro-benzamide 
• 25412-75-3 4-nitrobenzamidine 
• 50445-50-6 N-ethyl-4-nitrobenzamide 
• 7409-30-5 p-nitrobenzylamine 
• 56222-10-7 N-(4-nitrobenzyl)acetamide 
• 60-35-5 acetamide 
• 555-16-8 4-nitrobenzaldehdye 
• 1147869-37-1 ethyl (2E)-3-(acetylamino)-3-(4-nitrophenyl)-2-phenylacrylate 
• 1147869-38-2 ethyl (2Z)-3-(acetylamino)-3-(4-nitrophenyl)-2-phenylacrylate 
• 127-09-3 sodium acetate 

Downstream Products

• 1361032-68-9 3-methyl-5-(4-nitrophenyl)-1-phenyl-1H-1,2,4-triazole 

Relevant academic research and scientific papers

Transition-Metal- and Halogen-Free Oxidation of Benzylic sp 3 C-H Bonds to Carbonyl Groups Using Potassium Persulfate

Aryl carbonyl compounds including acetophenones, benzophenones, imides, and benzoic acids are prepared from benzyl substrates using potassium persulfate as oxidant with catalytic pyridine in acetonitrile under mild conditions. Neither transition metals nor halogens are involved in the reactions.

Synthesis of 1,3,5-trisubstituted-1,2,4-triazoles by microwave-assisted N-acylation of amide derivatives and the consecutive reaction with hydrazine hydrochlorides

Facile and efficient procedures for the N-acylation reaction of amide derivatives with various acid anhydrides and the cyclization reaction of N-acylated amide derivatives with various hydrazine hydrochlorides were described. The reactions were carried out under microwave irradiation to give products in good yields in a few minutes. The synthesis of 1,3,5-trisubstituted- 1,2,4-triazoles from benzamides can also be accomplished in a simple one-pot sequential reaction.

BF3 · Et2O-induced decomposition of ethyl 2-diazo-3-hydroxy-3,3-diarylpropanoates in acetonitrile: A novel approach to 2,3-diaryl β-enamino ester derivatives

The BF3·Et2O-induced decomposition of ethyl 2-diazo-3-hydroxy-3,3-diarylpropanoates, prepared by the addition of a series of benzophenones to ethyl diazo(lithio)acetate, is reported and studied. By using acetonitrile as a solvent, the corresponding N-acyl β-enamino ester derivatives are obtained in good yields and with a diverse regioselectivity as the result of 1,2-aryl migration in the vinyl cation intermediates. The factors that govern the migratory aptitude as well as the mechanistic aspects of the reaction are discussed.

Highly efficient copper-catalyzed amidation of aldehydes by C-H activation

We have developed a highly efficient method for the copper-catalyzed amidation of aldehydes in the presence of N-bromosuccinimide (NBS). This method is simple, economical, and has practical advantages for synthesis of imides.

Novel chromium(VI) catalyzed oxidation of N-alkylamides to imides with periodic acid

A novel and practical procedure for preparation of imides is described using chromium(VI) oxide to catalyze the oxidation of N-alkylamides with periodic acid in the presence of acetic anhydride in acetonitrile.