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N,N'-dimethyl-5-nitro-pyrimidine-2,4-diamine is an organic compound with the chemical formula C6H9N5O2. It is a derivative of pyrimidine, a heterocyclic aromatic organic compound consisting of a six-membered ring with four carbon atoms and two nitrogen atoms. In this specific compound, two of the nitrogen atoms are substituted with methyl groups (-CH3), and the 5-position of the pyrimidine ring is substituted with a nitro group (-NO2). The compound is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, as well as its use as an intermediate in the production of dyes and pigments. Due to its reactivity and functional groups, it is essential to handle N,N'-dimethyl-5-nitro-pyrimidine-2,4-diamine with care, following proper safety protocols and guidelines.

5177-26-4

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5177-26-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5177-26-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,7 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 5177-26:
(6*5)+(5*1)+(4*7)+(3*7)+(2*2)+(1*6)=94
94 % 10 = 4
So 5177-26-4 is a valid CAS Registry Number.

5177-26-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-N,4-N-dimethyl-5-nitropyrimidine-2,4-diamine

1.2 Other means of identification

Product number -
Other names n,n'-dimethyl-5-nitropyrimidine-2,4-diamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5177-26-4 SDS

5177-26-4Relevant academic research and scientific papers

KINASE INHIBITORS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES

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Page/Page column 92, (2008/06/13)

The present invention relates to novel kinase inhibitors and modulator compounds useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferrably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

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Page/Page column 23-24, (2010/02/15)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly di

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