519141-14-1

Basic information

• Product Name: 3-benzyloxycarbonyl-1,3,4-trimethylpiperazine-2,5-dione
• Synonyms: 3-benzyloxycarbonyl-1,3,4-trimethylpiperazine-2,5-dione
• CAS NO: 519141-14-1
• Molecular Weight: 290.319
• Mol File: 519141-14-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-benzyloxycarbonyl-1,3,4-trimethylpiperazine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzyloxycarbonyl-1,3,4-trimethylpiperazine-2,5-dione(519141-14-1)
• EPA Substance Registry System: 3-benzyloxycarbonyl-1,3,4-trimethylpiperazine-2,5-dione(519141-14-1)

Safety Data

• Hazardous Substances Data: 519141-14-1(Hazardous Substances Data)

Upstream product

• 519141-03-8 1-methyl-3-benzyloxycarbonylpiperazine-2,5-dione 
• 865879-17-0 benzyl N-[N-t-butoxycarbonylsarcosyl]-2-benzyloxycarbonylglycinate 
• 865879-15-8 3-(ethoxycarbonyl)-1,4-dimethylpiperazine-2,5-dione 
• 519141-04-9 3-benzyloxycarbonyl-1,4-dimethylpiperazine-2,5-dione 
• 74-88-4 methyl iodide 
• 519141-10-7 3-benzyloxycarbonyl-1,3-dimethylpiperazine-2,5-dione 
• 865879-16-9 ethyl N-[N-benzyloxycarbonylsarcosyl]-2-ethoxycarbonylsarcosinate 
• 15014-25-2 malonic acid dibenzyl ester 
• 51118-40-2 dibenzyl 2-(hydroxyimino)malonate 
• 31661-15-1 dibenzyl aminomalonate 

Downstream Products

• 198877-45-1 1,4-dimethyl-3-methylenepiperazine-2,5-dione 
• 519141-18-5 3-methoxy-1,3,4-trimethylpiperazine-2,5-dione 
• 182067-63-6 1,3,4-trimethylpiperazine-2,5-dione 

Relevant articles and documents

The synthetic versatility of alkoxycarbonyl- and hydroxymethyl-piperazine- 2,5-diones

Alkoxycarbonylpiperazine-2,5-diones are versatile precursors for the α-functionalisation of piperazine-2,5-diones. The alkoxycarbonyl group activates the α-carbon position to alkylation reactions and this provides a mild and selective method for the extension of the carbon framework of piperazine-2,5-diones. In addition, the alkoxycarbonyl group can be converted to the carboxy group, which in turn can be 'deleted' or manipulated for the installation of carbon and/or heteroatom substituents where desired, the latter via N-acyliminium chemistry. We also demonstrate that hydroxymethylpiperazine-2, 5-diones complement carboxypiperazinediones as precursors for the generation of N-acyliminium ions.