51926-66-0Relevant articles and documents
Two Colour Photoflow Chemistry for Macromolecular Design
Barner-Kowollik, Christopher,Blinco, James P.,De Bruycker, Kevin,Van De Walle, Matthias
, p. 14143 - 14147 (2020/06/10)
We report a photochemical flow setup that exploits λ-orthogonal reactions using two different colours of light (λ1=350 nm and λ2=410 nm) in sequential on-line irradiation steps. Critically, both photochemically reactive units (a visi
OXIME COMPOUND AND HERBICIDE
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Paragraph 0240, (2019/07/31)
PROBLEM TO BE SOLVED: To provide a novel agrochemical, particularly a herbicide. SOLUTION: The present invention provides an oxime compound represented by formula (1) [where B is B-1 or the like, Q is NOR7, A is a hydrogen atom, C1-C6 alkyl or the like, R6 is a halogen atom, -N(R6c) R6d or the like, R6c and R6d are hydrogen atoms, R7 is a hydrogen atom, C1-C6 alkyl or the like, R10, R11 and R12 are hydrogen atoms, Z is C1-C6 alkyl or the like, q is an integer of 0-5] and a herbicide containing the same. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT
Monodentate Transient Directing Group Enabled Pd-Catalyzed Ortho-C-H Methoxylation and Chlorination of Benzaldehydes
Li, Feng,Zhou, Yirong,Yang, Heng,Wang, Ziqi,Yu, Qinqin,Zhang, Fang-Lin
supporting information, p. 3692 - 3695 (2019/05/24)
We report Pd-catalyzed ortho-C-H methoxylation and chlorination of benzaldehydes by employing monodentate transient directing groups (TDGs) as an alternative strategy to bidentate TDGs. More importantly, a single crystal of benzaldehyde imine ortho-cyclopalladium intermediate was successfully obtained, and its structure was unambiguously determined by X-ray diffraction, which clearly showed that it was a binuclear palladium species bridged by a pyridone ligand. The utility of this approach was further demonstrated through the synthesis of key intermediates of natural products and drugs.
Synthesis of oxygenated orthomethylbenzaldehydes via aryne [2+2] cycloaddition and benzocyclobutenol ring opening
Maturi, Mark M.,Ohmori, Ken,Suzuki, Keisuke
, p. 870 - 873 (2019/01/21)
Herein, a two-step procedure for the preparation of oxygenated ortho-methylbenzaldehyde derivatives, starting from commercially available bromoarenes, is described. The synthesis features the simultaneous and highly regioselective installation of both the methyl and the formyl group onto the benzene core via benzyne [2+2] cycloadditions with acetaldehyde lithium enolate to give the corresponding benzocyclobutenols in high yields. Bond-selective ring opening of the benzocyclobutenols under basic conditions in methanol delivers the title compounds.
Formylation of electron-rich aromatic rings mediated by dichloromethyl methyl ether and TiCl4: Scope and limitations
Ramos-Tomillero, Iván,Paradís-Bas, Marta,De Pinho Ribeiro Moreira, Ibério,Bofill, Josep María,Nicolás, Ernesto,Albericio, Fernando
supporting information, p. 5409 - 5422 (2015/05/13)
Here the aromatic formylation mediated by TiCl4 and dichloromethyl methyl ether previously described by our group has been explored for a wide range of aromatic rings, including phenols, methoxy- and methylbenzenes, as an excellent way to produce aromatic aldehydes. Here we determine that the regioselectivity of this process is highly promoted by the coordination between the atoms present in the aromatic moiety and those in the metal core.
2-BENZYL-BENZIMIDAZOLE COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF
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Page/Page column 47, (2015/05/19)
The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical comp
A direct and mild formylation method for substituted benzenes utilizing dichloromethyl methyl ether-silver trifluoromethanesulfonate
Ohsawa, Kosuke,Yoshida, Masahito,Doi, Takayuki
, p. 3438 - 3444 (2013/06/26)
A silver trifluoromethanesulfonate (AgOTf)-promoted direct and mild formylation of benzenes has been developed. The reaction utilizing dichloromethyl methyl ether (Cl2CHOMe) and AgOTf powerfully formylated various substituted benzenes under temperature conditions as low as -78 C without losing the protecting groups on the phenolic hydroxyl group.
Phenyl-substituted Bicyclooctane-1,3-dione Derivatives
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Page/Page column 63, (2011/04/13)
The invention relates to novel compounds of the formula (I) in which X, Y, Z, A, B and G have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides. Moreover, the inv
Studies on oxidations with IBX: Oxidation of alcohols and aldehydes under solvent-free conditions
Moorthy, Jarugu Narasimha,Singhal, Nidhi,Venkatakrishnan
, p. 5419 - 5424 (2007/10/03)
A variety of allylic and benzylic alcohols are oxidized to their respective carbonyl compounds with IBX under solvent-free conditions at ca. 60-70°C. It has also been found that some of the aromatic aldehydes also undergo oxidation when heated with IBX at 90°C under solvent-free conditions; notably, this transformation does not occur under the otherwise identical but heterogeneous conditions.
De novo design, synthesis, and evaluation of novel nonsteroidal phenanthrene ligands for the estrogen receptor
Schmidt, Jonathan M.,Mercure, Julie,Tremblay, Gilles B.,Pagé, Martine,Kalbakji, Aida,Feher, Miklos,Dunn-Dufault, Robert,Peter, Markus G.,Redden, Peter R.
, p. 1408 - 1418 (2007/10/03)
Although there are many estrogen receptor antagonists with improved tissue selectivity profiles compared with tamoxifen, optimal tissue selectivity has not yet been demonstrated. As such there is still a need for additional diversity and new chemical scaf
