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1,2-DIPHENYL-1H-IMIDAZOLE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

52179-66-5

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52179-66-5 Usage

Class

Imidazole derivatives

Type

Heterocyclic aromatic compound

Structure

Contains two phenyl rings

Industrial Applications

a. Building block in the synthesis of other organic compounds and pharmaceuticals
b. Corrosion inhibitor in the petroleum industry

Biological Activities

a. Antifungal properties
b. Antimicrobial properties

Potential Applications

a. Fluorescent probe for detecting metal ions
b. Antitumor agent

Health Hazards

Use and handling require caution due to potential health risks

Check Digit Verification of cas no

The CAS Registry Mumber 52179-66-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,1,7 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 52179-66:
(7*5)+(6*2)+(5*1)+(4*7)+(3*9)+(2*6)+(1*6)=125
125 % 10 = 5
So 52179-66-5 is a valid CAS Registry Number.

52179-66-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-diphenylimidazole

1.2 Other means of identification

Product number -
Other names 1H-Imidazole,1,2-diphenyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52179-66-5 SDS

52179-66-5Relevant academic research and scientific papers

Phosphorescent cationic iridium complexes with phenyl-imidazole type cyclometalating ligands: A combined experimental and theoretical study on photophysical, electrochemical and electroluminescent properties

He, Lei,Wang, Zhen,Yang, Chunpeng,Duan, Lian,Tang, Ruiren,Song, Xiangzhi,Pan, Chunyue

, p. 76 - 83 (2016)

Phosphorescent cationic iridium complexes with phenyl-imidazole type cyclometalating ligands have been synthesized for the first time and their photophysical, electrochemical properties have been comprehensively investigated. By changing the ancillary lig

Palladium-catalyzed direct C2-arylation of azoles with aromatic triazenes

Liu, Can,Wang, Zhiming,Wang, Lei,Li, Pinhua,Zhang, Yicheng

, p. 9209 - 9216 (2019/11/05)

A highly efficient palladium-catalyzed arylation of azoles at the C2-position using 1-aryltriazenes as aryl reagents was developed. Azoles including oxazoles, thiazoles, imidazoles, 1,3,4-oxadiazoles, and oxazolines could react with 1-aryltriazenes smoothly to generate the corresponding products in good to excellent yields, and various substitution patterns were tolerated toward the reaction.

Phosphorescent Cyclometalated Platinum(II) aNHC Complexes

Soellner, Johannes,Strassner, Thomas

, p. 15603 - 15612 (2018/09/25)

The synthesis and characterization of the first bidentate C^C* cyclometalated platinum(II) complexes based on abnormal N-heterocyclic carbenes (aNHC) is presented. The aNHC ligand precursors are prepared from benzonitriles and anilines to form 1,2,3-trisu

N-arylation of indoles with aryl halides using copper/glycerol as a mild and highly efficient recyclable catalytic system

Yadav, Dilip Kumar T.,Rajak, Sanil S.,Bhanage, Bhalchandra M.

, p. 931 - 935 (2014/02/14)

A simple, efficient, and inexpensive copper catalyzed protocol has been developed for cross-coupling of indoles with aryl halides by using glycerol as a green recyclable solvent and DMSO as an additive. The reaction was carried out at low catalyst loading furnishing various N-aryl indoles in good to excellent yield. This copper/glycerol mixture was recycled up to four runs without any loss in its catalytic activity.

N-arylation of indoles with aryl halides using copper/glycerol as a mild and highly efficient recyclable catalytic system

Yadav, Dilip Kumar T.,Rajak, Sanil S.,Bhanage, Bhalchandra M.

, p. 931 - 935 (2015/02/19)

A simple, efficient, and inexpensive copper catalyzed protocol has been developed for cross-coupling of indoles with aryl halides by using glycerol as a green recyclable solvent and DMSO as an additive. The reaction was carried out at low catalyst loading furnishing various N-aryl indoles in good to excellent yield. This copper/glycerol mixture was recycled up to four runs without any loss in its catalytic activity.

Copper-catalyzed CuAAC/intramolecular C-H arylation sequence: Synthesis of annulated 1,2,3-triazoles

Jeyachandran, Rajkumar,Potukuchi, Harish Kumar,Ackermann, Lutz

, p. 1771 - 1777,7 (2020/09/16)

Step-economical syntheses of annulated 1,2,3-triazoles were accomplished through copper-catalyzed intramolecular direct arylations in sustainable one-pot reactions. Thus, catalyzed cascade reactions involving [3 + 2]-azide-alkyne cycloadditions (CuAAC) and C-H bond functionalizations provided direct access to fully substituted 1,2,3-triazoles with excellent chemo- and regioselectivities. Likewise, the optimized catalytic system proved applicable to the direct preparation of 1,2-diarylated azoles through a one-pot C-H/N-H arylation reaction.

Efficient and highly regioselective direct C-2 arylation of azoles, including free (NH)-imidazole, -benzimidazole and -indole, with aryl halides

Bellina, Fabio,Calandri, Chiara,Cauteruccio, Silvia,Rossi, Renzo

, p. 1970 - 1980 (2007/10/03)

The Pd- and Cu-mediated reaction of a large variety of π-electron sufficient heteroarenes, which include free (NH)-imidazoles, -benzimidazole and -indole, with aryl iodides under ligandless and base-free conditions provides regioselectively the required 2-arylheterocycle derivatives in high yields. 2-Aryl-1-phenyl-1H-imidazoles can also be prepared by a one-pot domino HALEX and Pd- and Cu-mediated arylation reactions of 1-phenyl-1H-imidazole with activated and unactivated aryl bromides under base-free and ligandless conditions. The protocol for the synthesis of 2-arylazoles involving the use of aryl iodides has been found to be suitable for the efficient preparation of three bioactive compounds and a key intermediate in the synthesis of a heparanase inhibitor.

Organic light emitting materials and devices

-

, (2008/06/13)

An organic light emitting device is provided. The device has an anode, a cathode and an organic layer disposed between the anode and the cathode. The organic layer comprises a compound further comprising one or more arylimidazole, aryltriazole, or aryltet

Regiocontrolled synthesis of 1,2-diaryl-1H-imidazoles by palladium- and copper-mediated direct coupling of 1-aryl-1H-imidazoles with aryl halides under ligandless conditions

Bellina, Fabio,Cauteruccio, Silvia,Mannina, Luisa,Rossi, Renzo,Viel, Stephane

, p. 693 - 703 (2007/10/03)

A large variety of 1,2-diaryl-1H-imidazoles, including a selective COX-2 inhibitor, have been regioselectively synthesised in moderate to high yields by direct coupling of 1-aryl-1H-imidazoles with aryl iodides or bromides in DMF in the presence of CsF an

Synthesis, structure-activity relationships at the GABAA receptor in rat brain, and differential electrophysiological profile at the recombinant human GABAA receptor of a series of substituted 1,2-diphenylimidazoles

Asproni, Battistina,Talani, Giuseppe,Busonero, Fabio,Pau, Amedeo,Sanna, Sebastiano,Cerri, Riccardo,Mascia, Maria Paola,Sanna, Enrico,Biggio, Giovanni

, p. 2638 - 2645 (2007/10/03)

A series of new 1,2-diphenylimidazole derivatives (1a-x) were synthesized and evaluated for their ability to potentiate γ-aminobutyric acid (GABA)-evoked currents in Xenopus laevis oocytes expressing recombinant human GABAA receptors. Many of t

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