52372-89-1

Basic information

• Product Name: Phosphinothioic acid, diphenyl-, S-butyl ester
• CAS NO: 52372-89-1
• Molecular Formula: C16H19OPS
• Molecular Weight: 290.366
• Mol File: 52372-89-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Phosphinothioic acid, diphenyl-, S-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinothioic acid, diphenyl-, S-butyl ester(52372-89-1)
• EPA Substance Registry System: Phosphinothioic acid, diphenyl-, S-butyl ester(52372-89-1)

Safety Data

• Hazardous Substances Data: 52372-89-1(Hazardous Substances Data)

Upstream product

• 109-65-9 1-bromo-butane 
• 14278-72-9 diphenylthiophosphinic acid 
• 108-86-1 bromobenzene 
• 109-79-5 n-butanethiol 
• 4559-70-0 Diphenylphosphine oxide 
• 2386-60-9 perfluoro-1-butanesulfonyl fluoride 
• 1079-66-9 chloro-diphenylphosphine 
• 1499-21-4 Diphenylphosphinic chloride 

Downstream Products

• 1366610-54-9 (E)-1-(diphenylphosphinyl)-2-butylthio-2-(p-tolyl)ethene 
• 1366610-53-8 (Z)-1-(diphenylphosphinyl)-2-butylthio-2-(p-tolyl)ethene 
• 1366610-56-1 (E)-1-(diphenylphosphinyl)-2-butylthio-2-(p-anisyl)ethene 
• 1366610-55-0 (Z)-1-(diphenylphosphinyl)-2-butylthio-2-(p-anisyl)ethene 
• 1879-14-7 1-(n-butylthio)vinylbenzene 
• 1366610-52-7 C₂₄H₂₅OPS 
• 1366610-51-6 C₂₄H₂₅OPS 
• 1366610-40-3 (E)-1-(diphenylphosphinyl)-2-butylthio-1-octene 
• 1366610-39-0 (Z)-1-(diphenylphosphinyl)-2-butylthio-1-octene 
• 1366610-61-8 (E)-3-(diphenylphosphinyl)-2-butylthio-1-phenyl-1-propene 
• 1366610-62-9 (Z)-3-(diphenylphosphinyl)-2-butylthio-1-phenyl-1-propene 
• 1366610-48-1 (Z)-1-(diphenylphosphinyl)-2-butylthio-3-phenyl-1-propene 
• 172221-61-3 (oct-1-yn-1-yl)diphenylphosphine oxide 
• 1366610-45-8 methyl (E)-6-(diphenylphosphinyl)-5-butylthio-5-hexenoate 

Relevant articles and documents

Tf2O/DMSO-Promoted P-O and P-S Bond Formation: A Scalable Synthesis of Multifarious Organophosphinates and Thiophosphates

A Tf2O/DMSO-based system for the dehydrogenative coupling of a wide range of alcohols, phenols, thiols, and thiophenols with diverse phosphorus reagents has been developed. This metal- and strong-oxidant-free strategy provides a facile approach to a great variety of organophosphinates and thiophosphates. The simple reaction system, good functional-group tolerance, and broad substrate scope enable the application of this method to the modification of natural products and the direct synthesis of bioactive molecules and flame retardants.

Novel method for preparing thiophosphonate through oxidative dehydrogenation coupled reaction of copper-catalyzed diarylphosphine oxide and mercaptan

The invention provides a method for efficiently and highly selectively synthesizing thiophosphonate derivatives containing different substituted functional groups. According to the method, cuprous iodide is used as a catalyst, 2,2 '-dipyridyl is used as a ligand, pyridine is used as alkali, oxygen is used as an oxidizing agent, diarylphosphine oxide and a mercaptan compound are used as reaction substrates, and an organic solvent is added into a reaction system. The method has the advantages that the catalyst and the oxidant are cheap and easily available; substrate applicability is high; reaction conditions are mild, safe and reliable; the selectivity of the obtained target product is close to 100%; and the yield of the target products is as high as 90% or above. The method overcomes the defects of poor reaction selectivity, complex reaction steps, low yield, need for reagents harmful to the environment and the like in traditional synthesis of thiophosphonate derivatives, and has goodindustrial application prospects. The invention also provides the corresponding thiophosphonate derivatives containing different substituted functional groups at the same time.

Metal- and base-free reductive coupling reaction of P(O)-H with aryl/alkyl sulfonyl chlorides: a novel protocol for the construction of P-S-C bonds

Novel and efficient synthesis of S-aryl/alkyl phosphinothioates from P(O)-H and aryl/alkyl sulfonyl chlorides under metal- and base-free conditions is described. This reaction provides an alternative strategy for the construction of P-S-C bonds in moderate to excellent yields. Moreover, this method can be readily applied to gram-scale preparation.