524714-06-5 Usage
Uses
Used in Pharmaceutical Industry:
(2S,3E)-4-Bromo-1-(4-fluorophenoxy)-3-buten-2-ol is used as an intermediate in the preparation of Lipoxin analogs for the pharmaceutical industry. Lipoxins are bioactive molecules that play a crucial role in the resolution of inflammation and have potential therapeutic applications in various inflammatory diseases. (2S,3E)-4-Bromo-1-(4-fluorophenoxy)-3-buten-2-ol's unique structure allows it to be a key component in the synthesis of these valuable analogs, contributing to the development of new drugs targeting inflammation-related conditions.
Used in Chemical Synthesis:
(2S,3E)-4-Bromo-1-(4-fluorophenoxy)-3-buten-2-ol can also be utilized as a building block in the synthesis of other complex organic molecules, particularly in the field of chemical research and development. Its distinct functional groups and structural features make it a valuable starting material for creating novel compounds with potential applications in various industries, such as agrochemicals, materials science, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 524714-06-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,2,4,7,1 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 524714-06:
(8*5)+(7*2)+(6*4)+(5*7)+(4*1)+(3*4)+(2*0)+(1*6)=135
135 % 10 = 5
So 524714-06-5 is a valid CAS Registry Number.
524714-06-5Relevant academic research and scientific papers
Novel 3-Oxa Lipoxin A4 Analogues with Enhanced Chemical and Metabolic Stability Have Anti-inflammatory Activity in Vivo
Guilford, William J.,Bauman, John G.,Skuballa, Werner,Bauer, Shawn,Wei, Guo Ping,Davey, David,Schaefer, Caralee,Mallari, Cornell,Terkelsen, Jennifer,Tseng, Jih-Lie,Shen, Jun,Subramanyam, Babu,Schottelius, Arndt J.,Parkinson, John F.
, p. 2157 - 2165 (2007/10/03)
Lipoxin A4 (LXA4) is a structurally and functionally distinct natural product called an eicosanoid, which displays immunomodulatory and anti-inflammatory activity but is rapidly metabolized to inactive catabolites in vivo. A previous
Synthesis of methyl (5S,6R,7E,9E,11Z,13E,15S)-16-(4-fluorophenoxy)-5,6,15-trihydroxy-7,9,11, 13-hexadecatetraenoate, an analogue of 15R-lipoxin A4
Phillips, Eifion D.,Chang, Hui-Fang,Holmquist, Christopher R.,McCauley, John P.
, p. 3223 - 3226 (2007/10/03)
We describe a method for the synthesis of methyl (5S,6R,7E,9E,11Z,13E,15S)-16-(4-fluorophenoxy)-5,6,15-trihydroxy-7,9,11, 13-hexadecatetraenoate, a compound that has been described as a metabolically stable analogue of 15R-lipoxin A4.
