5257-08-9

Usage

Uses

Used in Pharmaceutical Applications:
Glycozolinine is used as an antimicrobial and antifungal agent for treating bacterial and fungal infections. Its natural origin and potential to target a wide range of pathogens make it a valuable alternative to conventional antibiotics and antifungal medications.
Used in Anticancer Applications:
Glycozolinine is used as an anticancer agent, showing potential in inhibiting the growth of certain cancer cells. Further research is needed to explore its mechanism of action and its potential synergistic effects with existing cancer therapies.
Used in Agricultural Applications:
Glycozolinine is used as a natural pesticide and insecticide, offering an eco-friendly alternative to synthetic chemicals. Its potential to control pests and diseases in crops without causing harm to the environment or non-target organisms highlights its value in sustainable agriculture.
Ongoing research is essential to fully understand the potential uses and safety profile of Glycozolinine, paving the way for its integration into various industries and applications.

Upstream product

• 91377-13-8 6-hydroxy-3-methyl-1,2,3,4-tetrahydrocarbazole 
• 5234-30-0 glycozoline 
• 1312447-85-0 3-methoxy-6-methyl-9-tosyl-9H-carbazole 
• 16077-10-4 N-benzyl-5-methoxyisatin 
• 39755-95-8 5-methoxyisatine 
• 91377-11-6 4-methylcyclohexane-1,2-dione-1-(4'-hydroxy-phenyl)hydrazone 
• 91377-12-7 6-hydroxy-3-methyl-1-oxo-1,2,3,4-tetrahydrocarbazole 
• 123-30-8 4-amino-phenol 
• 151692-21-6 (3-bromo-4-chloro-phenoxy)-tert-butyl-dimethyl-silane 
• 126644-72-2 1-<(tert-butyldimethylsilyl)oxy>-4-chlorobenzene 
• 14618-59-8 N-(tert-butoxycarbonyl)-4-methylaniline 
• 106-49-0 p-toluidine 
• 39253-43-5 N-(4-methylphenyl)-4-methoxyaniline 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 5234-30-0 glycozoline 
• 4630-20-0 3-Methyl-9H-carbazole 

Relevant academic research and scientific papers

A one-pot "back-to-front" approach for the synthesis of benzene ring substituted indoles using allylboronic acids

Synthesis of only benzene ring functionalized indoles and poly-substituted carbazoles is reported via a one-pot triple cascade benzannulation protocol. Usage of differently substituted and readily accessible allylboronic acids as a 3-carbon annulating partner enables diverse aliphatic and aromatic substitution patterns, which is still a daunting task. This scalable synthetic protocol tolerates broad scope, thus enabling further downstream modifications. As an application, carbazole based natural products glycozoline and glycozolinol were synthesized. This journal is

Divergent and Orthogonal Approach to Carbazoles and Pyridoindoles from Oxindoles via Indole Intermediates

The previously unexplored Grignard addition to oxindoles provides a regiospecific approach to 2- and 2,3-disubstituted indole derivatives in high yields via a one-pot aromatization driven dehydration pathway. This method allows a convenient preparation of diallyl indoles that are used as ring-closing metathesis (RCM) precursors for the orthogonal synthesis of pyrido[1,2-a]indoles and carbazoles. The synthetic utility of this method is illustrated by the synthesis of a microtubulin inhibitor and naturally occurring carbazole alkaloids.

Transition metals in organic synthesis - Part 83#: Synthesis and pharmacological potential of carbazoles

A series of carbazole derivatives with promising pharmacological properties has been prepared using either an iron-mediated or a palladium-catalyzed synthetic approach. The carbazole alkaloids carbazoquinocin C, carbazomadurin A and B, epocarbazolin A and

Transition metals in organic synthesis, part 82.1 First total synthesis of methyl 6-methoxycarbazole-3-carboxylate, glycomaurrol, the anti-TB active micromeline, and the furo[2,3-c]carbazole alkaloid eustifoline-D

The palladium(0)-catalyzed animation followed by palladium(II)-catalyzed oxidative cyclization of the resulting diarylamine provides a short route to a series of 6-oxygenated carbazole alkaloids: glycozoline, 3-formyl-6- methoxycarbazole, methyl 6-methoxy

A REGIOSPECIFIC SYNTHESIS OF CARBAZOLES VIA CONSECUTIVE PALLADIUM-CATALYZED CROSS-COUPLING AND ARYNE-MEDIATED CYCLIZATION

A regiospecific synthesis of carbazoles has been developed using palladium-catalyzed cross-coupling of N-(tert-butoxycarbonyl)-2-tributylstannylanilines with 2- or 3-bromochlorobenzene followed by aryne-mediated cyclization as the key reactions.The carbazole alkaloids, glycozolinine and glycozolidine, were synthesized using this procedure.

Structure and Synthesis of Glycozolinol, a New Carbazole Alkaloid from Glycosmis pentaphylla (Retz) DC.

Glycozolinol, a new carbazole alkaloid isolated from Glycosmis pentaphylla (Retz) DC. has been formulated as 6-hydroxy-3-methylcarbazole (I) based on physical data, chemical reactions and spectral evidences.The structure (I) has been confirmed by synthesis.