52605-99-9

Basic information

• Product Name: 5,6-Dimethoxynicotinaldehyde
• Synonyms: 5,6-Dimethoxynicotinaldehyde;5,6-diMethoxypyridine-3-carbaldehyde;5,6-Dimethoxynicotildehyde
• CAS NO: 52605-99-9
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.16196
• Mol File: 52605-99-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 277.8±35.0 °C(Predicted)
• Appearance: /
• Density: 1.174±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 2.45±0.10(Predicted)
• CAS DataBase Reference: 5,6-Dimethoxynicotinaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-Dimethoxynicotinaldehyde(52605-99-9)
• EPA Substance Registry System: 5,6-Dimethoxynicotinaldehyde(52605-99-9)

Safety Data

• Statements: 43
• Safety Statements: 36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 52605-99-9(Hazardous Substances Data)

Usage

General Description

5,6-Dimethoxynicotinaldehyde is a chemical compound with a molecular formula of C9H11NO3. It is categorized under organic compounds known as pyridinecarboxaldehydes, characterized by a pyridine ring bearing an aldehyde and falls under the nicotinaldehyde group of compounds. Its systematic name in the IUPAC nomenclature is 5,6-dimethoxy pyridine-3-carboxaldehyde. It is soluble in organic solvents but little information is available about its specific usage and properties due to its specialized nature in various chemical research and reactions. Its physical and chemical properties may vary based on its state (solid, liquid, or gas) and temperature.

Upstream product

• 1428797-03-8 2,3-dimethoxy-5-vinylpyridine 
• 52605-98-8 5-bromo-2,3-dimethoxypyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 6636-78-8 2-chloro-3-hydroxypyridine 
• 52605-97-7 2,3-dimethoxypyridine 
• 52605-96-6 2-chloro-3-methoxypyridine 

Downstream Products

• 1620205-06-2 2,6-bis-(5,6-dimethoxypyridin-3-ylmethylene)cyclohexanone 
• 1581767-74-9 (5,6-dimethoxypyridin-3-yl)(4-fluorophenyl)methanol 
• 1581767-75-0 5-(4-fluorobenzyl)-2,3-dimethoxypyridine 
• 1581767-28-3 5-(4-fluorobenzyl)-3-hydroxypyridin-2(1H)-one 
• 106331-49-1 1-(3,4,5-trimethoxyphenyl)-4-(2,3-dimethoxypyrid-5-yl)-1,4-butanedione 

Relevant articles and documents

D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF

The present invention relates to compounds of Formula (I): or a pharmaceutically acceptable salt thereof, wherein: each of A, B, C, D, and E, independently, is C, N, N—H, O, S, or absent is a single bond or a double bond; each of X, Y, and Z, independentl

Synthesis and evaluation of analogues of the tuberculosis drug bedaquiline containing heterocyclic B-ring units

Analogues of bedaquiline where the phenyl B-unit was replaced with monocyclic heterocycles of widely differing lipophilicity (thiophenes, furans, pyridines) were synthesised and evaluated. While there was an expected broad positive correlation between lipophilicity and anti-TB activity, the 4-pyridyl derivatives appeared to have an additional contribution to antibacterial potency. The majority of the compounds were (desirably) more polar and had higher rates of clearance than bedaquiline, and showed acceptable oral bioavailability, but there was only limited (and unpredictable) improvement in their hERG liability.

FSH RECEPTOR ANTAGONISTS

The invention relates to FSH receptor antagonist according to general formula (I) or a pharmaceutically acceptable salt thereof and to a pharmaceutical composition containing the same. The compounds can be used for the treatment and prevention of endometriosis, for the treatment and prevention of pre-menopausal and peri-menopausal hormone-dependent breast cancer, for contraception, and for the treatment of uterine fibroids and other menstrual-related disorders