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Trimethylsilyl methioninate is a chemical compound derived from methionine, an essential amino acid, by the addition of a trimethylsilyl (TMS) group. The TMS group is a common protecting group in organic chemistry, used to shield functional groups from unwanted reactions. In the case of trimethylsilyl methioninate, the TMS group is attached to the sulfur atom of the methionine molecule, forming a stable and less reactive compound. This modification can be useful in various chemical and biological applications, such as protecting the thiol group during peptide synthesis or studying the reactivity of the methionine residue in proteins. The compound is typically synthesized by reacting methionine with a trimethylsilyl donor, such as trimethylsilyl chloride or trimethylsilyl azide, in the presence of a suitable base.

5269-64-7

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5269-64-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5269-64-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,2,6 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5269-64:
(6*5)+(5*2)+(4*6)+(3*9)+(2*6)+(1*4)=107
107 % 10 = 7
So 5269-64-7 is a valid CAS Registry Number.

5269-64-7Relevant academic research and scientific papers

Efficient "One-Pot" Synthesis of N-Trityl Amino Acids

Barlos, Kleomenis,Papaioannou, Dionysios,Theodoropoulos, Dimitrios

, p. 1324 - 1326 (2007/10/02)

A sequential procedure has been developed whereby neutral amino acids 1 were tritylated via their corresponding trimethylsilyl esters 2 to afford, after mild hydrolysis, N-trityl amino acids 3 in high yields and purity.Hydroxy amino acids 4 were preferent

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