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4,7-Dichloro-1-indanone is a chemical compound characterized by the molecular formula C9H5Cl2O. It is a white crystalline solid that serves as a valuable building block in the synthesis of pharmaceuticals and agrochemicals. As a diketone, it features two adjacent carbonyl groups, and the chlorine atoms present in its structure contribute to its utility as an intermediate for the production of a range of organic compounds. Additionally, 4,7-Dichloro-1-indanone is recognized for its potential biological activity, making it a subject of research for possible therapeutic applications. However, due to its hazardous nature, it is crucial to handle and store 4,7-Dichloro-1-indanone with proper care.

52977-63-6

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52977-63-6 Usage

Uses

Used in Pharmaceutical Industry:
4,7-Dichloro-1-indanone is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its unique structure, which includes two carbonyl groups and chlorine atoms, makes it a versatile building block in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 4,7-Dichloro-1-indanone is utilized as a starting material for the production of different agrochemicals. Its chemical properties allow it to be a valuable component in the creation of pesticides and other agricultural chemicals.
Used in Organic Chemistry Research:
4,7-Dichloro-1-indanone is employed as a research compound in organic chemistry. Its potential biological activity and the presence of functional groups make it an interesting subject for studies aimed at discovering new organic reactions and applications.
Used in the Development of Therapeutic Agents:
Due to its potential biological activity, 4,7-Dichloro-1-indanone is used in the research and development of therapeutic agents. Scientists are exploring its properties to understand its possible applications in medicine and to develop new treatments for various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 52977-63-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,9,7 and 7 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 52977-63:
(7*5)+(6*2)+(5*9)+(4*7)+(3*7)+(2*6)+(1*3)=156
156 % 10 = 6
So 52977-63-6 is a valid CAS Registry Number.

52977-63-6Relevant academic research and scientific papers

Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists

Zhou, Zhang-Lin,Kher, Sunil M.,Cai, Sui Xiong,Whittemore, Edward R.,Espitia, Stephen A.,Hawkinson, Jon E.,Tran, Minhtam,Woodward, Richard M.,Weber, Eckard,Keana, John F. W.

, p. 1769 - 1780 (2007/10/03)

A series of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones (QXs) related to licostinel (Acea 1021) was synthesized and evaluated as antagonists for the glycine site of the N-methyl-D-asparate (NMDA) receptor. The in vitro potency of these

SYNTHESIS AND REACTIVITY OF POLYCHLOROCYCLOPENTANONES

Buyck, L. De,Kimpe, N. De,Verhe, R.,Courtheyn, D.,Schamp, N.

, p. 1043 - 1060 (2007/10/02)

Selective chlorination methods were elaborated for the conversion of cyclopentanone into 2,2,5,5-tetrachloro-, 2,2,3,5,5-pentachloro- and 2,2,3,3,5,5-hexachlorocyclopentanone.Dimethylformamide-hydrogen chloride mixtures served as catalysts for enolization and for dehydrochlorination to chlorinated cyclopentenones.The reactivity of the polychlorocyclopentanones was tested towards zinc (in acetic acid, methanol or acetone) and towards bases in protic solvents.A number of chlorinated cyclopentenones, substitution products and open chain compounds (Grob elimination) were obtained in good yields.

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