5299-64-9

Basic information

• Product Name: N-NONANOYLMORPHOLINE
• Synonyms: 1-(4-morpholino)-1-nonanon;1-Nonanone, 1-(4-morpholino)-;4-(1-oxononyl)-morpholin;4-(1-oxononyl)morpholine;4-nonanoyl-morpholin;4-Nonanoylmorpholine;AI 318284;ai318284
• CAS NO: 5299-64-9
• Molecular Formula: C13H25NO2
• Molecular Weight: 227.34
• Mol File: 5299-64-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 369.06°C (rough estimate)
• Flash Point: 169.9°C
• Appearance: /
• Density: 0.9796 (rough estimate)
• Vapor Pressure: 2.74E-05mmHg at 25°C
• Refractive Index: 1.4410 (estimate)
• CAS DataBase Reference: N-NONANOYLMORPHOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-NONANOYLMORPHOLINE(5299-64-9)
• EPA Substance Registry System: N-NONANOYLMORPHOLINE(5299-64-9)

Safety Data

• Hazardous Substances Data: 5299-64-9(Hazardous Substances Data)

Usage

Uses

N-Nonanoylmorpholine are known to have irritant effects.

InChI:InChI=1/C13H25NO2/c1-2-3-4-5-6-7-8-13(15)14-9-11-16-12-10-14/h2-12H2,1H3

Upstream product

• 110-91-8 morpholine 
• 629-27-6 1-Iodooctane 
• 201230-82-2 carbon monoxide 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 112-05-0 nonanoic acid 
• 111-66-0 oct-1-ene 
• 764-85-2 Nonanoyl chloride 

Relevant articles and documents

Tandem Photoredox Catalysis: Enabling Carbonylative Amidation of Aryl and Alkylhalides

We report a new visible-light-mediated carbonylative amidation of aryl, heteroaryl, and alkyl halides. A tandem catalytic cycle of [Ir(ppy)2(dtb-bpy)]+ generates a potent iridium photoreductant through a second catalytic cycle in the presence of DIPEA, which productively engages aryl bromides, iodides, and even chlorides as well as primary, secondary, and tertiary alkyl iodides. The versatile in situ generated catalyst is compatible with aliphatic and aromatic amines, shows high functional-group tolerance, and enables the late-stage amidation of complex natural products.

Flexible and Chemoselective Oxidation of Amides to α-Keto Amides and α-Hydroxy Amides

A suite of flexible and chemoselective methods for the transition-metal-free oxidation of amides to α-keto amides and α-hydroxy amides is presented. These highly valuable motifs are accessed in good to excellent yields and stereoselectivities with high functional group tolerance. The utility of the method is showcased by the formal synthesis of a potent histone deacetylase inhibitor.

Leishmanicidal potential of N-substituted morpholine derivatives: Synthesis and structure-activity relationships

A series of N-substituted morpholines 2-20 was synthesised by reacting various acid chlorides and alkyl halides with morpholine (1). All of the synthesised compounds 2-20 were screened for their leishmanicidal effects using amphotericin B (IC50 = 0.24 μg L-1) and pentamidine (IC50 = 2.56 μg mL-1) as standards and a structure-activity relationship (SAR) study was established. The compounds 2 (IC50 = 48 μg mL-1), 3 (IC50 = 30.0 μg mL-1), 10 (IC50 = 41.0 μg mL-1), 15 (IC50 = 33.0 μg mL-1), 16 (IC50 = 35.0 μg mL-1) and 20 (IC50 = 47.0 μg mL-1) showed weak leishmanicidal activities.