53174-98-4

Usage

Uses

Used in Pharmaceutical Industry:
THIENO[2,3-B]PYRIDINE-2-CARBALDEHYDE is used as a key building block in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with improved efficacy and selectivity. It is particularly valuable in the creation of compounds with antifungal and antimicrobial properties, which can be used to treat a wide range of infections.
Used in Agrochemical Industry:
In the agrochemical industry, THIENO[2,3-B]PYRIDINE-2-CARBALDEHYDE serves as an essential component in the production of various agrochemicals. Its incorporation into these products can enhance their effectiveness in controlling pests and diseases, thereby improving crop yields and food security.
Used in Organic Synthesis:
THIENO[2,3-B]PYRIDINE-2-CARBALDEHYDE is used as a versatile intermediate in organic synthesis. Its unique structure allows for the formation of a wide range of functional materials, including polymers, dyes, and sensors. Its reactivity and compatibility with various chemical reactions make it a valuable tool for the synthesis of complex organic compounds.
Used in Research and Development:
THIENO[2,3-B]PYRIDINE-2-CARBALDEHYDE is utilized in research and development for its potential biological activities. Scientists are studying its antifungal and antimicrobial properties to explore its potential applications in medicine and agriculture. Additionally, its unique structure makes it an interesting subject for fundamental research in chemistry and materials science.

InChI:InChI=1/C8H5NOS/c10-5-7-4-6-2-1-3-9-8(6)11-7/h1-5H

Upstream product

• 272-23-1 thieno[2,3-b]pyridine 
• 68-12-2 N,N-dimethyl-formamide 
• 131337-81-0 2-(hydroxymethyl)thieno<2,3-b>pyridine 
• 154650-88-1 methyl thieno[2,3-b]pyridine-2-carboxylate 
• 36404-88-3 2-chloro-3-carbaldehydepyridine 

Downstream Products

• 1402598-28-0 N-((2-(methylsulfanyl)phenyl)(thieno[2,3-b]pyridin-2-yl)methyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide 
• 1402598-27-9 N-((2-methoxyphenyl)(thieno[2,3-b]pyridin-2-yl)methyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide 
• 1402598-26-8 N-(phenyl(thieno[2,3-b]pyridin-2-yl)methyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide 
• 933751-19-0 thieno[2,3-b]pyridin-2-ylmethanamine 

Relevant academic research and scientific papers

Metal free coupling of heteroaryl N-tosylhydrazones and thiols: Efficient synthesis of sulfides

A metal free coupling of heteroaromatic N-tosylhydrazones with thiols is presented. A convenient synthetic route to synthesize heteroaryl N-tosylhydrazones is also showed. Valuable thioethers with pyrroles, pyridines, thieno[2,3-b]pyridines, imidazo[1,2-a]pyridines, and 6H-thieno[2,3-b]pyrroles derivatives were synthesized in good yields. This coupling reaction can be carried out in a one-pot fashion and scaled up to the gram scale by using heteroaryl aldehydes, without the need to isolate the N-tosylhydrazone.

SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS

The present invention relates to novel spiro-oxadiazoline compounds that are suitable as agonists or partial agonists of a7-nAChR, and pharmaceutical compositions of the same, methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering a spiro-oxadiazoline cx7-nAChR agonist or partial agonist, to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.

Enantioselective Synthesis of 5-LO Inhibitors Using a Gulofuranose Auxiliary

The pure R-(+)-enantiomer of 5-lipoxygenase inhibitor Zileuton was prepared by diastereoselective methyl Grignard addition to an aldonitrone bearing a D-gulofuranose-derived chiral auxiliary.Addition of the Lewis acid trimethylaluminum leads to a reversal of the alkylation stereochemistry and the potent pyrido analogue, R-(+)-RS-27871 was prepared in this way from an L-gulofuranose-derived nitrone.