5326-21-6

Basic information

• Product Name: Benzamide, N,N-1,6-hexanediylbis-
• CAS NO: 5326-21-6
• Molecular Formula: C₂₀H₂₄N₂O₂
• Molecular Weight: 324.423
• Mol File: 5326-21-6.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 606.5°Cat760mmHg
• Flash Point: 214.2°C
• Density: 1.092g/cm³
• CAS DataBase Reference: Benzamide, N,N-1,6-hexanediylbis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N-1,6-hexanediylbis-(5326-21-6)
• EPA Substance Registry System: Benzamide, N,N-1,6-hexanediylbis-(5326-21-6)

Safety Data

• Hazardous Substances Data: 5326-21-6(Hazardous Substances Data)

Upstream product

• 93-97-0 benzoic acid anhydride 
• 124-09-4 1,6-Hexanediamine 
• 10364-94-0 1-benzoylimidazole 
• 6055-52-3 hexane-1,6-diamine dihydrochloride 
• 23405-15-4 benzoic acid N-hydroxysuccinimide ester 
• 100-52-7 benzaldehyde 
• 98-88-4 benzoyl chloride 
• 3009-40-3 N¹,N²-dibenzylidenehexane-1,6-diamine 
• 1002-23-9 NN'-di(isobutylidene)-1,6-diaminohexane 
• 50-00-0 formaldehyd 
• 55-21-0 benzamide 
• 642470-70-0 N-(5-cyano-pentyl)-benzamide 
• 99036-29-0 2,5-Bis-benzoylaminomethyl-thiophen 

Downstream Products

• 629-03-8 1 ,6-dibromohexane 
• 30070-99-6 N,N'-dibenzyl-1,6-diaminohexane 
• 93300-59-5 C₂₂H₂₈N₂O₂ 
• 100-47-0 benzonitrile 
• 2163-00-0 1,6-dichlorohexane 

Relevant articles and documents

N-Acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides: Highly selective and efficient reagents for acylation of amines in water

A variety of N-acyl-N-(4-chlorophenyl)-4-nitrobenzenesulfonamides (1a-e) were synthesized in one pot from 4-chloroaniline under solvent-free conditions and have been developed as chemoselective N-acylation reagents. Selective protection of primary amines in the presence of secondary amines, acylation of aliphatic amines in the presence of aryl amines, and monofunctionalization of primary-secondary diamines as well as selective N-acylation of amino alcohols using these reagents are described. All of the acylation reactions were carried out in water as a green solvent. High stability and easy preparation of these acylating reagents are other advantages of this method.

CDI-mediated monoacylation of symmetrical diamines and selective acylation of primary amines of unsymmetrical diamines

A highly efficient and green protocol for monoacylation of symmetrical diamines and chemoselective acylation of primary amines of unsymmetrical diamines has been developed.

Imidazole-catalyzed monoacylation of symmetrical diamines

Figure Presented. An imidazole-catalyzed protocol for monoacylation of symmetrical diamines has been developed. The protocol gave selective monoacylation of aliphatic (cyclic and acyclic) primary and secondary diamines. In the reaction, imidazole acts as both catalyst and a leaving group. Different monoacylated piperazines and other diamines were synthesized at room temperature in an ethanol/water solvent system.