5326-49-8

Upstream product

• 74586-53-1 3-bromo-5-methylaniline 
• 108-24-7 acetic anhydride 
• 127-19-5 N,N-dimethyl acetamide 
• 64-19-7 acetic acid 

Downstream Products

• 1263376-30-2 3,4-dibromo-5-methyl-aniline 
• 78238-11-6 3-bromo-5-acetylaminobenzoic acid 
• 337535-59-8 N-[4'-[1-hydroxy-2-methyl-1-(1-trityl-1H-imidazol-4-yl)propyl]-5-methyl[1,1'-biphenyl]-3-yl]acetamide 
• 603-78-1 2,3-dibromobenzoic acid 
• 42237-85-4 3-amino-5-bromobenzoic acid 
• 61563-25-5 2,3-dibromotoluene 

Relevant academic research and scientific papers

NEAR-INFRARED NERVE-SPARING BENZO[C]PHENOXAZINE FLUOROPHORES

Provided are near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures.

AMINOTRIAZOLES FOR THE TREATMENT OF DEMYELINATING DISEASES

The invention relates to triazole compounds of formula (I') or pharmaceutically acceptable salts thereof, useful as modulators of demyelinating diseases: wherein A is selected from the group consisting of (i), (ii), (iii), (iv), (v), and (vi) The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention, methods of using the compositions and kits thereof in the treatment of various demyelinating and neurodegenerative diseases, including multiple sclerosis.

Convenient N-acetylation of amines in N,N-dimethylacetamide with N,N-carbonyldiimidazole

Dimethylacetamide (DMAc) acts as an efficient source of acetyl and dimethylamine gas in the presence of N,N-carbonyldiimidazole (CDI). Addition of amines to the reaction mixture delivers the corresponding amides in good to excellent yields. The acetylation of amines reported herein, which relies on the in situ generation of N-acetylimidazole on warming of DMAc with CDI at 120-125 °C, serves as a convenient alternative to other acetylation methods.