533-62-0

Usage

Purification Methods

Crystallise the acid from water. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 1 pp 211-213, Vol 3 p 2422 1961.]

InChI:InChI=1/C5H9NO5/c6-4(5(10)11)2(7)1-3(8)9/h2,4,7H,1,6H2,(H,8,9)(H,10,11)

Upstream product

• 7647-01-0 hydrogenchloride 
• 10035-10-6 hydrogen bromide 
• 98197-90-1 3-(2,5-dioxo-imidazolidin-4-yl)-acrylic acid 
• 64-17-5 ethanol 
• 996-75-8 diethyl 2-nitroso-3-ketoglutarate 
• 19883-13-7 DL-threo-N-acetyl-3-hydroxy-glutamic acid diethyl ester 
• 102076-70-0 DL-erythro-N-benzoyl-3-hydroxy-glutamic acid diethyl ester 
• 105-50-0 diethyl 1,3-acetonedicarboxylate 
• 7683-74-1 DL-erythro-3-hydroxy-glutamic acid diethyl ester; hydrochloride 
• 97315-78-1 diethyl α-aminoacetonedicarboxylate 
• 7705-08-0 iron(III) chloride 
• 19883-13-7 diethyl N-acetyl-3-hydroxyglutamate 
• 7683-73-0 diethyl 3-hydroxyglutamate 
• 97336-09-9 diethyl 2-acetamido-3-ketoglutarate 

Downstream Products

• 131216-18-7 2-{4-[2-(2,4-Diamino-pteridin-6-yl)-ethyl]-benzoylamino}-3-hydroxy-pentanedioic acid 
• 107-43-7 betaine 
• 328-50-7 α-ketoglutaric acid 
• 7664-41-7 ammonia 

Relevant academic research and scientific papers

Kutznerides 1-4, depsipeptides from the actinomycete Kutzneria sp. 744 inhabiting mycorrhizal roots of Picea abies seedlings

Bioassay-guided fractionation of culture supernatants of the actinomycete Kutzneria sp. 744 resulted in the isolation of four new depsipeptides (1-4). Structure analysis revealed the general structure: cyclo[2-(1-methylcyclopropyl) -D-glycine-(2S,3aR,8aS)

L-threo- and L-erythro-3-Fluoroglutamic Acids. Synthesis by Fluorodehydroxylation and Enzymatic Resolution.

threo- and erythro-3-fluoroglutamic acids were prepared by fluorodehydroxylation of N-acetyl-3-hydroxyglutamic acids according to Kollonitsch.Following ion exchange column separation of the diastereoisomers, enzymatic deacylation by acylase I afforded optically pure L-isomers of the 3-fluoroglutamic acid.Assignment of structure was achieved by correlation with cis- and trans-3-fluoropyroglutamic acids.The results indicate predominant inversion of configuration during the fluorodehydroxylation reaction.