5333-12-0

Upstream product

• 538-44-3 4,4-dimethyl-1-phenyl-1-penten-3-one 
• 71-43-2 benzene 
• 91-01-0 1,1-Diphenylmethanol 
• 17510-46-2 3,3-dimethyl-2-(trimethylsilyl)oxy-1-butene 
• 84850-50-0 3,3-dimethyl-2-{[(1,1-dimethylethyl)dimethylsilyl]oxy}-1-butene 
• 507-19-7 t-butyl bromide 
• 606-83-7 3,3-Diphenylpropionic acid 
• 72531-41-0 4,4-Dimethyl-3-oxo-pentanoic Acid 
• 853-83-8 N-tosyldiphenylmethylamine 
• 100865-93-8 O-diphenylmethyl 2,2,2-trichloroacetimidate 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 90-99-3 diphenylchloromethane 
• 31463-55-5 5,5-Dimethyl-1,3,3-triphenyl-hexane-1,4-dione 

Downstream Products

• 4812-78-6 (Z)-3-[1-(2,2-Diphenyl-ethyl)-2,2-dimethyl-propylcarbamoyl]-acrylic acid 
• 844-39-3 Dimethyl-4,4 diphenyl-1,1 pentene-1 one-3 
• 4812-77-5 2,2-Dimethyl-1-(2,2-diphenylethyl)-propylamine 
• 94743-38-1 2-bromo-4,4-dimethyl-1,1-diphenyl-pentan-3-one 

Relevant academic research and scientific papers

Unprecedented alkylation of silicon enolates with alcohols via carbenium ion formations catalyzed by tin hydroxide-embedded montmorillonite

The solid acid, tin hydroxide-embedded montmorillonite, catalyzes the unprecedented alkylation of various silicon enolates with primary, secondary and tertiary benzylic alcohols as well as secondary allylic alcohols. The acid catalysis of Sn-Mont was not only higher than that of the other ion-exchanged montmorillonites (M-Mont; M?=?H, Ti, Fe and Al), but also higher than that of the typical homogeneous acid catalysts such as BF3·OEt2, TMSOTf and TfOH.

Ni-catalyzed reductive coupling of alkyl acids with unactivated tertiary alkyl and glycosyl halides

This work highlights Ni-catalyzed reductive coupling of alkyl acids with alkyl halides, particularly sterically hindered unactivated tertiary alkyl bromides for the production of all carbon quaternary ketones. The reductive strategy is applicable to α-selective synthesis of saturated, fully oxygenated C-acyl glycosides through easy manipulations of the readily available sugar bromides and alkyl acids, avoiding otherwise difficult multistep conversions. Initial mechanistic studies suggest that a radical chain mechanism (cycle B, Scheme 1) may be plausible, wherein MgCl2 promotes the reduction of NiII complexes.

Catalytic decarboxylative alkylation of β-keto acids with sulfonamides via the cleavage of carbon-nitrogen and carbon-carbon bonds

An efficient decarboxylative alkylation reaction of β-keto acids with N-benzylic or N-allylic sulfonamides has been developed, for the first time, through sequential cleavage of carbon-nitrogen and carbon-carbon bonds in the presence of 10 mol% of FeCl3.

One-pot hydroxy group activation/carbon-carbon bond forming sequence using a Bronsted base/bronsted acid system

A new sequential two-step multicatalytic strategy is presented consisting in the efficient DBU-catalysed trichloroacetimidation of an alcohol followed by a ditriflylamine (Tf2NH)-catalysed intermolecular alkylation by silicon-based nucleophiles and C-H nucleophiles. The distinct feature of the trichloroacetimidate group allows use of weaker acid catalysts such as 1,1′-bi-2-naphthol (BINOL)-derived phosphoric acid, pointing out the possible development of an enantioselective variant. This unprecedented sequential one-pot Bronsted base-Bronsted acid catalysis further expands the synthetic scope of the trichloroacetimidate group. Copyright

Synthese de tertiobutylcetones α-azotees de type =N-C(R1)(R2)-CO-C(CH3)3

The α-nitrogen-ketones 2, 3 and 4 were prepared from α-bromoketones.These were synthesized by the bromination of the ketones which had been obtained by the pinacolone or benzyltertiobutylketone alkylation from the corresponding halo-derivatives.We have observed that the bromination of the ketones depends to some extent upon the nature of these compounds.