5333-22-2

Usage

Physical state at room temperature

Yellow solid

Usage

UV filter in sunscreen and skincare products

Function

Absorbs and dissipates UV radiation

Protection spectrum

Broad-spectrum against UVA and UVB rays

Structural feature

Two benzoyl groups attached to a pentane-1,5-dione backbone

UV-absorbing properties

Resulting from its structure

Safety

Considered safe for use in skincare products within specified concentrations by regulatory bodies

Upstream product

• 108-55-4 glutaric anhydride, 
• 108-88-3 toluene 
• 2873-74-7 gloutaric dichloride 
• 7446-70-0 aluminium trichloride 
• 630-20-6 1,1,1,2-tetrachoroethane 
• 157367-59-4 1,5-Di-p-tolyl-6,7-dioxa-bicyclo[3.2.2]nonane 
• 157367-55-0 4,4'-(hepta-1,6-diene-2,6-diyl)bis(methylbenzene) 
• 170647-13-9 2,4-bis-(4-methylbenzoyl)-1,5-di-p-tolylpentane-1,5-dione 
• 50-00-0 formaldehyd 
• 3594-36-3 1,3-bis(p-methylphenyl)-1,3-propanedione 
• 67-56-1 methanol 

Downstream Products

• 93641-11-3 bis(di-p-tolyl-2,6 thiopyrannylidene)-4:4' 
• 93641-13-5 bis(di-p-tolyl-2,6 thiopyrannylidene)-4:4'-TCNQ 
• 157367-55-0 4,4'-(hepta-1,6-diene-2,6-diyl)bis(methylbenzene) 

Relevant academic research and scientific papers

Asymmetric hydrogenation of 1,4-diketones: facile synthesis of enantiopure 1,4-diarylbutane-1,4-diols

Owing to the biological significance and great synthetic value of 1,4-diarylbutane-1,4-diols and their derivatives, increasingly considerable attention has been paid to developing effective synthetic methods for chiral 1,4-diarylbutane-1,4-diols. We herei

Cobalt(II)-Catalyzed Stereoselective Olefin Isomerization: Facile Access to Acyclic Trisubstituted Alkenes

Stereoselective synthesis of trisubstituted alkenes is a long-standing challenge in organic chemistry, due to the small energy differences between E and Z isomers of trisubstituted alkenes (compared with 1,2-disubstituted alkenes). Transition metal-catalyzed isomerization of 1,1-disubstituted alkenes can serve as an alternative approach to trisubstituted alkenes, but it remains underdeveloped owing to issues relating to reaction efficiency and stereoselectivity. Here we show that a novel cobalt catalyst can overcome these challenges to provide an efficient and stereoselective access to a broad range of trisubstituted alkenes. This protocol is compatible with both mono- and dienes and exhibits a good functional group tolerance and scalability. Moreover, it has proven to be a useful tool to construct organic luminophores and a deuterated trisubstituted alkene. A preliminary study of the mechanism suggests that a cobalt-hydride pathway is involved in the reaction. The high stereoselectivity of the reaction is attributed to both a π-πstacking effect and the steric hindrance between substrate and catalyst.

Electrooxidative formation of 1,2-diaroylcyclopropanes from 1,3-diaroylpropanes in the presence of KI

Various 1,2-diaroylcyclopropanes were obtained in good yields by the indirect electrochemical oxidation of 1,3-diaroylpropanes in the presence of catalytic amounts of KI under very mild conditions.

Synthesis, Fe(II)-induced degradation, and antimalarial activities of 1,5-diaryl-6,7-dioxabicyclo[3.2.2]nonanes: Direct evidence for nucleophilic O-1,2-aryl shifts

1,5-Diaryl-6,7-dioxabicyclo[3.2.2]nonanes 1a-d (1a: Ar=p-FC6H4, 1b: Ar=Ph, 1c: Ar=p-MeC6H4, 1d: Ar=p-MeOC6H4) were prepared by a modified method of photo-electron transfer oxygenation, and the reactions of 1 with FeBr2 were investigated under various conditions. The Fe(II)-induced degradation of 1 afforded various rearrangement products and fragmentation products through competitive single electron transfer (SET) and Lewis acid pathways. Direct evidence for the O-1,2-aryl shift was obtained by the isolation of rearrangement products, 1-aryloxy-5-aryl-8-oxabicyclo[3.2.1]octanes 8. The degradation mechanism was proposed and the in vitro antimalarial activities were also evaluated.

Novel photo-rearrangement of 1,5-di(p-methoxyphenyl)-6,7-dioxabicyclo[3.2.2]nonane through an O-neophyl-type 1,2-aryl shift: Evidence for a 1,6-dioxyl diradical intermediate

Photolysis and thermolysis of 1,5-diaryl-6,7-dioxabicyclo[3.2.2]nonane 1a-c (a: Ar=p-MeOC6H4, b: Ar=p-MeC6H4, c: Ar=Ph) were investigated. (p-Methoxyphenyl)-substituted 1a underwent a novel photo-initiated O-neophyl-type 1,2-aryl shift to afford 1-(p-methoxyphenyl)oxy-5-(p-methoxyphenyl)-8-oxabicyclo[3.2.1]octane 7a along with a small amount of 1-(p-methoxyphenyl)-3-(2-(4′-methoxyphenyl)tetrahydrofuran-2-yl) propan-1-one 4a through an 1,6-dioxyl diradical intermediate, while the thermolysis mainly afforded the 1,5-di(p-methoxyphenyl)pentan-1,5-dione 5a and 1,4-di(p-methoxyphenyl)butan-1,4-dione 8a.

Photoinduced Electron Transfer (PET) cyclization and photooxygenation of 2,6-diaryl-1,6-heptadienes and 2,7-diaryl-1,7-octadienes

The 2,6-diaryl-substituted 1,6-heptadienes 3a-c and the 2,7-diaryl-substituted 1,7-octadienes 4a-b were cleanly converted into the corresponding anellated cyclobutanes 5 and 6, resp., when irradiated under photoelectron-transfer conditions (9,10-dicyanoanthracene in acetonitrile). Only for 4c did the rearranged compound 7c become the dominant photoproduct. Oxygen trapping experiments with formation of endoperoxides 8, 9 were successful in the case of the electron-rich substrates 3b, c and 4c. VCH Verlagsgesellschaft mbH, 1996.

Highly Selective Aldol Reaction of Dibenzoylmethanes with Formaldehyde Catalyzed by Cobalt Schiff Base Complex under Neutral Conditions

Coordinatively saturated hydroxocobalt(III) Schiff base complexes catalyze highly selective aldol reaction of dibenzoylmethanes with formaldehyde in methanol to give 1,3-dibenzoylpropanes, resulting from retro-Claisen reaction of 1,1,3,3-tetrabenzoylpropanes, which are obtained quantitatively in dichlorometane.Coordinatively saturated cobalt(III) Schiff base complexes ligating a substrate anion as a monodentate ligand is found to be the reactive species.