53503-30-3

Basic information

• Product Name: (2,4-dimethylquinolin-3-yl)(phenyl)methanone
• Synonyms: (2,4-dimethylquinolin-3-yl)(phenyl)methanone
• CAS NO: 53503-30-3
• Molecular Weight: 247.296
• Mol File: 53503-30-3.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: (2,4-dimethylquinolin-3-yl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (2,4-dimethylquinolin-3-yl)(phenyl)methanone(53503-30-3)
• EPA Substance Registry System: (2,4-dimethylquinolin-3-yl)(phenyl)methanone(53503-30-3)

Safety Data

• Hazardous Substances Data: 53503-30-3(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 64-17-5 ethanol 
• 529-23-7 o-aminobenzaldehyde 
• 93-91-4 1-phenylbutan-1,3-dione 
• 56969-57-4 C₁₇H₁₃NO₄ 
• 552-89-6 2-nitro-benzaldehyde 
• 271-58-9 anthranil 
• 495-40-9 propiophenone 
• 5344-90-1 2-Aminobenzyl alcohol 
• 35660-91-4 (E)-1-phenyl-2-buten-1-one 
• 1621416-93-0 (Z)-1-phenyl-3-{2-[(E)-(2-phenylethenyl)]phenylamino}but-2-en-1-one 
• 107522-67-8 3-benzoyl-2-methyl-quinoline-4-carboxylic acid 
• 27652-35-3 (E)-2-styrylaniline 

Downstream Products

• 91-63-4 2-methylquinoline 
• 65-85-0 benzoic acid 
• 115533-96-5 (3-Cyano-1-phenyl-pyrrolo[3,4-b]quinolin-2-yl)-acetic acid 
• 53326-91-3 3-benzoyl-2-quinolinecarboxaldehyde 
• 101444-22-8 (2-methyl-[3]quinolyl)-phenyl ketone oxime 

Relevant articles and documents

Cascade Reaction of α, β-Unsaturated Ketones and 2-Aminoaryl Alcohols for the Synthesis of 3-Acylquinolines by a Copper Nanocatalyst

3-Acylquinolines possess widespread applications in functional chemicals. However, the convenient and selective synthesis of such important substructures has to date remained a challenge. Herein, we report a method to access 3-acylquinolines from α, β-unsaturated ketones and 2-aminoaryl alcohols in one pot with a copper nanocatalyst supported on nitrogen-silica-doped carbon (Cu/N?SiO2?C). Mechanistically, the construction of the product involves a cascade procedure including radical-type oxidation of 2-aminoaryl alcohols, aza-Michael addition and annulation. This developed protocol proceeds with merits of mild reaction conditions, good functional group tolerance, earth-abundant and reusable copper catalyst, easily available stocks and O2 as the sole oxidant, which provides an alternative way for the sustainable synthesis of quinoline derivatives. (Figure presented.).

Synthesizing method of aromatic pyridinopyridine compound

The invention discloses a synthesizing method of an aromatic pyridinopyridine compound, and belongs to the technical field of organic synthesizing. According to the technical scheme, the characteristics of the synthesizing method refers to the description. The method is simple, efficient, convenient to operate, mild in conditions, and wide in substrate applying scope.

Manganese(III) acetate mediated oxidative radical cyclizations of N -(2-alkenylaryl)-substituted enamines

A method has been developed for the synthesis of highly functionalized quinolines from readily available N-(2-alkenylaryl)-substituted enamines via a 6-exo-trig radical cyclization of an imine radical. Several useful functional groups including morpholinocarbonyl, benzoyl, and cyano, are compatible with the reaction conditions. Under the Mn(II)/Co(II)/O2 redox system, these N-(2-alkenylaryl)enamines were also converted into the corresponding quinolines effectively. This strategy was further applied to related 1,4-naphthoquinone derivatives, and benzo[b]acridine-6,11-diones were formed in good yields.