5356-99-0

Basic information

• Product Name: BENZYL(CHLOROMETHYL)DIMETHYLSILANE 97
• Synonyms: BENZYL(CHLOROMETHYL)DIMETHYLSILANE 97
• CAS NO: 5356-99-0
• Molecular Formula: C₁₀H₁₅ClSi
• Molecular Weight: 198.7646
• Mol File: 5356-99-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 120-124 °C40 mm Hg(lit.)
• Flash Point: 214 °F
• Appearance: /
• Density: 1.01 g/mL at 25 °C(lit.)
• Vapor Pressure: 2.74E-12mmHg at 25°C
• Refractive Index: n20/D 1.519(lit.)
• CAS DataBase Reference: BENZYL(CHLOROMETHYL)DIMETHYLSILANE 97(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL(CHLOROMETHYL)DIMETHYLSILANE 97(5356-99-0)
• EPA Substance Registry System: BENZYL(CHLOROMETHYL)DIMETHYLSILANE 97(5356-99-0)

Safety Data

• Statements: 29
• Safety Statements: 43
• RIDADR: UN 3398 4.3/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 5356-99-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C25H21ClFNO2/c1-3-29-24-14-19(12-20(15-28)21-6-4-5-7-23(21)27)13-22(26)25(24)30-16-18-10-8-17(2)9-11-18/h4-14H,3,16H2,1-2H3

Upstream product

• 100-39-0 benzyl bromide 
• 1719-57-9 Chloro(chloromethyl)dimethylsilane 
• 6921-34-2 benzylmagnesium chloride 

Downstream Products

• 49759-13-9 benzyldimethylsilylmethyl magnesium chloride 
• 188579-12-6 2-t-butyl-4-[(dimethylbenzylsilyl)methyloxy]phenol 
• 37110-39-7 β-(benzyldimethylsilyl)ethanol 
• 123463-27-4 (S)-5-chloro-1-phenylpentan-1-ol 
• 123537-30-4 (S)-2-phenyltetrahydro-2H-pyran 
• 65488-06-4 (S)-4-chloro-1-phenyl-1-butanol 
• 16133-83-8 (S)-2-phenyltetrahydrofuran 
• 123463-24-1 (S)-1-{[((S)-1,2-Diphenyl-ethyl)-dimethyl-silanyl]-methyl}-2-methoxymethyl-pyrrolidine 
• 123485-52-9 (S)-1-{[((S)-6-Iodo-1-phenyl-hexyl)-dimethyl-silanyl]-methyl}-2-methoxymethyl-pyrrolidine 
• 123463-25-2 (S)-1-{[((S)-5-Chloro-1-phenyl-pentyl)-dimethyl-silanyl]-methyl}-2-methoxymethyl-pyrrolidine 
• 123485-57-4 (S)-1-{[((S)-4-Chloro-1-phenyl-butyl)-dimethyl-silanyl]-methyl}-2-methoxymethyl-pyrrolidine 
• 123463-22-9 (S)-1-{[Dimethyl-((S)-1-phenyl-butyl)-silanyl]-methyl}-2-methoxymethyl-pyrrolidine 
• 123463-23-0 (S)-1-{[Dimethyl-((S)-1-phenyl-propyl)-silanyl]-methyl}-2-methoxymethyl-pyrrolidine 
• 123463-21-8 (S)-1-{[Dimethyl-((S)-1-phenyl-ethyl)-silanyl]-methyl}-2-methoxymethyl-pyrrolidine 

Relevant articles and documents

Amphipathic coating for modulating cellular adhesion composition and methods

The present invention provides an anti-thrombogenic and cellular-adhesion coating composition for blood-contacting surfaces. The coating comprises a covalent complex of from 1 to 30 hydrophobic silyl moieties of Formula I: wherein R1is an Csub

Benzylic lithium compounds: The missing link in carbon-lithium covalency. Dynamics of ion reorientation, rotation around the ring-benzyl bond, and bimolecular C-Li exchange

Benzyllithium compounds, hitherto assumed from NMR data to consist of ion pairs, have been found to exhibit spin coupling between 13C and directly bound 6Li under conditions wherein bimolecular carbon - lithium bond exchange is too slow to average the coupling constants. These conditions involved the use of species in which lithium is internally solvated or of dilute solutions (0.005 M) of benzyllithium-13C-6Li (enriched at Cα) at low temperature. The low values of 1J(13C-6Li), 3-4 Hz, imply a small detectable degree of C-Li covalence with the arrangement around Cα distorted from coplanarity. The C-Li bonds in benzyllithium are concluded to lie in a continuum of C-Li covalency between the many monomeric species in which 1J(13C-6Li) is 16 ± 1 Hz and separated ion pairs. NMR line shape analysis of data for internally solvated benzyllithium 2b provides quantitative insight into the dynamics of intramolecular reorientation of coordinated lithium with respect to the benzyl plane, rotation around the ring-Cα bond, and bimolecular carbon-lithium bond exchange, listed in order of widely different increasing rates, the activation parameters being ΔH? (kcal/mol) and ΔS? (eu) in the same order: 14 and 6.6; 6.4 and -14; 10.8 and -21.