53636-17-2Relevant articles and documents
Simple one-pot process for the bioresolution of tertiary amino ester protic ionic liquids using subtilisin
Brossat, Maude,Moody, Thomas S.,Taylor, Stephen J.C.,Wiffen, Jonathan W.
experimental part, p. 2112 - 2116 (2010/02/28)
An efficient hydrolase-catalyzed bioresolution of tertiary amino ester protic ionic liquids has been demonstrated. Protic ionic liquids have been prepared in one step from the corresponding tertiary amino alcohols by treatment with butyric anhydride. Afte
Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups
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, (2008/06/13)
A process for preparing optically active secondary alcohols of the general formula (3), [wherein R1 is linear lower alkyl, an aromatic ring group, or the like; A is CH2NR2R3 or the like; n is an integer of 0 to 2; and * represents an asymmetric carbon atom] by asymmetrically hydrogenating a ketone compound of the general formula (1) having nitrogenous or oxygen functional group at any of the a-, β- and γ-positions, with selectivity among functional groups by the use of a ruthenium/optically active bidentate phosphine/diamine complex as the catalyst in the presence of hydrogen alone or together with a base. The optically active secondary alcohols obtained by the process are useful as drugs and intermediates for the preparation of drugs.
Asymmetric hydrogenation of amino ketones using chiral RuCl2(diphophine)(1,2-diamine) complexes [12]
Ohkuma, Takeshi,Ishii, Dai,Takeno, Hiroshi,Noyori, Ryoji
, p. 6510 - 6511 (2007/10/03)
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