53657-63-9

Upstream product

• 104-55-2 3-phenyl-propenal 
• 60-34-4 methylhydrazine 
• 21023-97-2 cis-1-phenyl-2-(methylazo)cyclopropane 
• 21023-97-2 trans-1-phenyl-2-(methylazo)cyclopropane 
• 14371-10-9 (E)-3-phenylpropenal 
• 112349-80-1 1,5-diphenyl-tetrahydro-pyrazolo[1,2-a]pyrazole-2,6-dicarboxylic acid 

Downstream Products

• 70395-47-0 5-methyl-3,6c-diphenyl-(7ar)-5,6,7,7a-tetrahydro-pyrazolo[1,5-d][1,2,4]oxadiazole 
• 70395-47-0 5-methyl-3,6t-diphenyl-(7ar)-5,6,7,7a-tetrahydro-pyrazolo[1,5-d][1,2,4]oxadiazole 
• 95684-22-3 (3R,5R)-1-Methyl-3,5-diphenyl-pyrazolidine 
• 21939-23-1 1,2-dimethyl-trans-3,5-diphenylpyrazolidine 
• 3463-27-2 1-methyl-5-phenyl-1H-pyrazole 
• 21023-97-2 cis-1-phenyl-2-(methylazo)cyclopropane 
• 105229-78-5 3-Methylamino-3-phenyl-propionitrile 
• 21023-97-2 Methyl-((1R,2R)-2-phenyl-cyclopropyl)-diazene 
• 21023-97-2 trans-1-phenyl-2-(methylazo)cyclopropane 
• 95724-80-4 N¹-Methyl-1-phenyl-propane-1,3-diamine; hydrochloride 
• 70395-61-8 methyl-[1-phenyl-2-(3-phenyl-[1,2,4]oxadiazol-5-yl)-ethyl]-amine 
• 70395-63-0 5-styryl-3-phenyl-1,2,4-oxadiazole 
• 856680-16-5 1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazole 

Relevant academic research and scientific papers

Pyrazoline derivatives for treating cerebrovascular diseases

2-Pyrazoline derivatives of the formula (A): STR1 where R1 is a pyridyl, a pyrazyl or an alkoxy group; and R2 is a hydrogen atom, an alkyl, a pyridyl, a furyl, phenyl or a substituted phenyl group, and to a process for producing the same. Therapeutic agents for treating cerebrovascular diseases containing, as the active ingredient, a 2-pyrazoline derivative represented by the formula (G): STR2 where R3 is a hydrogen atom, an alkyl, acetyl, an alkoxycarbonyl, an amino, benzoyl, a substituted benzoyl, a pyridylcarbonyl, a furylcarbonyl, a thienylcarbonyl, a pyrazylcarbonyl, an N-substituted carbamoyl, an N-substituted thiocarbamoyl, or carboxy group; and R4 is a hydrogen atom, an alkyl, a pyridyl, a thienyl, a furyl, cyclohexyl, phenyl or a substituted phenyl group or a pharmaceutically acceptable salt thereof. These therapeutic agents cope with cerebral edemas in the acute stage of cerebral apoplexy and regulates the whole-body and intracranial body circulation, thereby protecting ischemic lesions and minimizing the spread to affected parts.

Photochemical Reinvestigation of a 5-Phenyl-2-pyrazoline and Its Product Azocyclopropanes

Irradiation of 1-methyl-5-phenyl-2-pyrazoline (1) affords the previously reported azocyclopropanes 2t and 3t; however, the major product of this reaction is β-(methylamino)-β-phenylpropionitrile (4).Although the azo linkage in 2t and 3t has the trans configuration, irradiation of either isomer causes azo trans -> cis isomerization, slower interconversion of the ring isomers, reversion to pyrazoline 1, and cleavage to styrene.Thermolysis of 2t proceeds twice as fast as that of 3t to interconvert the ring isomers and ultimately to afford exclusively 1.The rapid thermolysis rate of 2t and 3t relative to a model phenylvinylcyclopropane is interpreted in terms of an unusually high facile formation of the α-azo (hydrazonyl) radical.