537-91-7Relevant academic research and scientific papers
Palladium-Catalyzed Picolinamide-Directed Benzylic C(sp3)?H Chalcogenation with Diaryl Disulfides and Diphenyl Diselenide
Wang, Kai,Hou, Jiahao,Zhang, Changjun,Cheng, Ke,Bai, Renren,Xie, Yuanyuan
supporting information, p. 2947 - 2952 (2020/06/17)
The first palladium-catalyzed direct benzylic C(sp3)?H chalcogenation with diaryl disulfides and diphenyl diselenide has been established. The coupling reaction proceeds between the thioether radical and palladiumcycle intermediate. Picolinamide serves as an excellent directing group for the C?H activation of benzylic C(sp3)?H and can be easily removed. The current protocol exhibits a relatively broad substrate scope and high functional group compatibility. A mechanistic study indicates that palladium(IV) intermediate is probably formed during the course of the reaction. (Figure presented.).
Preparation method for symmetric diaryl disulfide
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, (2019/04/17)
The invention discloses a preparation method for symmetric diaryl disulfide. The preparation method comprises the following steps: using aromatic hydrocarbon as shown in a general formula (I) as a rawmaterial and reacting with chlorosulfonic acid to generate aryl chlorosulfonic acid, and reacting with sulfoxide chloride to synthesize aryl sulfonyl chloride as shown in a general formula (II); andpreparing the symmetric diaryl disulfide as shown in a general formula (III) under the action of a reducing agent through a reduction reaction by the aryl sulfonyl chloride as shown in the general formula (II). The disclosed preparation method for the symmetric diaryl disulfide has many advantages of low toxicity of the reaction raw material, short reaction time, cheap reagents and easy acquisition, convenient separation and purification and the like, and has very high application value and industrial production value.
Synthesis and nano-Pd catalyzed chemoselective oxidation of symmetrical and unsymmetrical sulfides
Li, Xing,Du, Jia,Zhang, Yongli,Chang, Honghong,Gao, Wenchao,Wei, Wenlong
, p. 3048 - 3055 (2019/03/21)
A highly chemoselective, efficient and nano-Pd catalyzed protocol for the rapid construction of sulfoxides and sulfones via the oxidation of symmetrical and unsymmetrical sulfides using H2O2 as an oxidant has been developed, respectively. The ready availability of starting materials, easy recovery and reutilization of the catalyst, wide substrate scope, and high yields make this protocol an attractive alternative. The process also involves the metal-free and microwave-promoted synthesis of symmetrical diarylsulfides, and FeCl3-mediated preparation of symmetrical diaryldisulfides through the reaction of arenediazonium tetrafluoroborates with Na2S·9H2O as a sulfur source. In addition, unsymmetrical sulfides were generated via the K2CO3-mediated reaction of arenediazonium tetrafluoroborates with symmetrical disulfides.
Conversion of organic halides to disulfanes using KCN and CS2
Abbasi, Mohammad,Nowrouzi, Najmeh,Borazjani, Saeedeh Ghassab
, p. 4251 - 4254 (2017/10/11)
A sulfur transfer reagent was produced in situ upon stirring a mixture of KCN and CS2 in DMF at r.t. for 15 min, which after heating with an alkyl halide or aryl halide and CuI gave the corresponding symmetric dialkyl or diaryl disulfide, respectively, in high to excellent yields.
Aryl diazonium salt and thioacetamide: A catalyst free, efficient blend of an inexpensive arylating agent with "s" surrogate for sulphide synthesis
Bhojane, Jeevan Manohar,Sarode, Sachin Ashok,Nagarkar, Jayashreemilind
, p. 90046 - 90050 (2016/10/07)
Novel, facile C-S and S-S bond coupling reactions were achieved by using an aryl diazonium salt as an arylating agent and thioacetamide as a sulphur surrogate. The reaction proceeds smoothly at room temperature without using any transition metal catalyst, ligand or base. Aryl diazonium salts undergo rapid reactions with thioacetamide at room temperature to give the desired products in a much shorter period than the previously reported metal catalysed protocols.
Investigation on the reduction of sulfonyl chlorides with sulfur dioxide in water as solvent
Zhao, Qian,Qian, Chao,Chen, Xin-Zhi
, p. 1547 - 1550 (2013/10/22)
An operationally simple and environmentally benign method for reductive coupling of sulfonyl chlorides to the corresponding disulfides has been developed. Sulfonyl chlorides can be rapidly reduced with SO2/KI/ H2SO4 system in moderate to good yields at 80 C in water. Graphical Abstract: [Figure not available: see fulltext.]
An improved method for the synthesis of disulfides by periodic acid and sodium hydrogen sulfite in water
Khan, Khalid M.,Taha, Muhammad,Rahim, Fazal,Ali, Muhammad,Jamil, Waqas,Perveen, Shahnaz,Iqbal Choudhary
experimental part, p. 415 - 419 (2011/03/22)
An improved method for the synthesis of disulfide in water by using periodic acid and sodium hydrogen sulfite was developed.
Synthesis of diaryl disulfides via the reductive coupling of arylsulfonyl chlorides
Kabalka, George W.,Reddy, Marepally Srinivasa,Yao, Min-Liang
scheme or table, p. 7340 - 7342 (2010/03/01)
A facile synthesis of diaryl disulfides from arylsulfonyl chlorides in the presence of triphenylphosphine has been developed.
Temperature-controlled selective reduction of arenesulfonyl chlorides promoted by samarium metal in DMF
Liu, Yongjun,Zhang, Yongmin
, p. 4291 - 4294 (2007/10/03)
Promoted by samarium in DMF, arenesulfonyl chlorides can be selectively reduced to diaryldisulfones, diarylthiosulfonates and diaryldisulfides in good to excellent yields by reaction temperature control without the need to pretreat or activate the metallic samarium.
Practical and scaleable syntheses of 3-hydroxythiophenol
Zhang, Mingbao,Ryckman, David,Chen, Guohua,MacMillan, Eric,Duquette, Jason
, p. 112 - 116 (2007/10/03)
3-Hydroxythiophenol is a versatile intermediate for the synthesis of medicinal and heterocyclic compounds. Two novel and practical syntheses of 3-hydroxythiophenol are achieved using readily available and inexpensive starting materials. An overall cost comparison of these syntheses is also given.
