537030-20-9Relevant academic research and scientific papers
Synthesis and glycosidase inhibitory activity of 7-deoxycasuarine
Carmona, Ana T.,Whigtman, Richard H.,Robina, Inmaculada,Vogel, Pierre
, p. 3066 - 3073 (2003)
Reaction of 1,4-anhydro-2,3,5-tri-O-benzyl-1-deoxy-1-imino-D-arabinitol N-oxide (8) with allyl alcohol produced a 3.6:1 mixture of the two pyrrolo[1,2-b]isoxazole derivatives 13 and 14. The major adduct 13 was converted to 7-deoxycasuarine (7), a potent,
Discovery of human hexosaminidase inhibitors by in situ screening of a library of mono- and divalent pyrrolidine iminosugars
Bojarová, Pavla,Carmona, Ana T.,K?en, Vladimír,Kulik, Natalia,Mészáros, Zuzana,Martínez-Bailén, Macarena,Moreno-Vargas, Antonio J.,Pingitore, Valeria,Robina, Inmaculada,Slámová, Kristyna
, (2022/02/14)
Two libraries of mono- and dimeric pyrrolidine iminosugars were synthesized by CuAAC and (thio)urea-bond-forming reactions from the respective azido/aminohexylpyrrolidine iminosugar precursors. The resulting monomeric and dimeric compounds were screened f
Total syntheses of hyacinthacine A2 and 7-deoxycasuarine by cycloaddition to a carbohydrate derived nitrone
Cardona, Francesca,Faggi, Enrico,Liguori, Francesca,Cacciarini, Martina,Goti, Andrea
, p. 2315 - 2318 (2007/10/03)
Practical syntheses of nitrone 8 by two different approaches from sugars are reported. Its use as a versatile intermediate in highly selective 1,3-dipolar cycloaddition reactions constitutes the key step for novel total syntheses of hyacinthacine A2
