537030-25-4Relevant academic research and scientific papers
Synthesis, biological evaluation and docking studies of casuarine analogues: Effects of structural modifications at ring B on inhibitory activity towards glucoamylase
Bonaccini, Claudia,Chioccioli, Matteo,Parmeggiani, Camilla,Cardona, Francesca,Lo Re, Daniele,Soldaini, Gianluca,Vogel, Pierre,Bello, Claudia,Goti, Andrea,Gratteri, Paola
experimental part, p. 5574 - 5585 (2011/02/19)
We report the total synthesis of a series of pyrrolizidine analogues of casuarine (1) and their 6-O-α-glucoside derivatives. The synthetic strategy is based on a totally regio- and stereoselective 1,3-dipolar cycloaddition of suitably substitutedalkenes a
Total syntheses of hyacinthacine A2 and 7-deoxycasuarine by cycloaddition to a carbohydrate derived nitrone
Cardona, Francesca,Faggi, Enrico,Liguori, Francesca,Cacciarini, Martina,Goti, Andrea
, p. 2315 - 2318 (2007/10/03)
Practical syntheses of nitrone 8 by two different approaches from sugars are reported. Its use as a versatile intermediate in highly selective 1,3-dipolar cycloaddition reactions constitutes the key step for novel total syntheses of hyacinthacine A2
