537030-28-7Relevant academic research and scientific papers
SmI2-mediated radical cross-couplings of α-hydroxylated aza-hemiacetals and N, S -acetals with α,β-unsaturated compounds: Asymmetric synthesis of (+)-hyacinthacine A2, (-)-uniflorine A, and (+)-7- epi -casuarine
Liu, Xue-Kui,Qiu, Shi,Xiang, Yong-Gang,Ruan, Yuan-Ping,Zheng, Xiao,Huang, Pei-Qiang
experimental part, p. 4952 - 4963 (2011/08/03)
The SmI2-mediated radical coupling reactions of β-hydroxylated pyrrolidine/piperidine aza-hemiacetals 8 and 9 and N,S-acetals 6 and 33 with α,β-unsaturated compounds are described. This method allows a rapid access to β-hydroxylated pyrrolidine
Total synthesis of (+)-hyacinthacine A2 based on SmI 2-induced nitrone umpolung
Desvergnes, Stephanie,Py, Sandrine,Vallee, Yannick
, p. 1459 - 1462 (2007/10/03)
(Chemical Equation Presented) A concise total synthesis of (+)-hyacinthacine A2, a polyhydroxylated pyrrolizidine alkaloid, is described using our recently discovered inversion of the C-N bond polarity in nitrones. In the key step, the diastere
