538-49-8

Basic information

• Product Name: 2-(2-Phenethenyl)pyridine
• Synonyms: (E)-2-Stilbazole;2-[(E)-2-Phenylvinyl]pyridine;2-[(E)-Styryl]pyridine;2-trans-Styrylpyridine
• CAS NO: 538-49-8
• Molecular Formula: C₁₃H₁₁N
• Molecular Weight: 181.23
• EINECS: 211-934-5
• Mol File: 538-49-8.mol
• Article Data: 138

Chemical Properties

• Melting Point: 91.5°C
• Boiling Point: 304.35°C (rough estimate)
• Flash Point: 127.2°C
• Appearance: /
• Density: 1.0147
• Vapor Pressure: 0.00196mmHg at 25°C
• Refractive Index: 1.6118 (estimate)
• CAS DataBase Reference: 2-(2-Phenethenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Phenethenyl)pyridine(538-49-8)
• EPA Substance Registry System: 2-(2-Phenethenyl)pyridine(538-49-8)

Safety Data

• Hazardous Substances Data: 538-49-8(Hazardous Substances Data)

Usage

General Description

2-(2-Phenethenyl)pyridine is a chemical compound with the formula C14H13N. It is a colorless to light yellow liquid with a strong, floral odor. 2-(2-Phenethenyl)pyridine is primarily used in the production of pharmaceuticals, flavoring agents, and fragrance ingredients. It is also commonly used as an intermediate in organic synthesis, particularly in the preparation of various pyridine derivatives. 2-(2-Phenethenyl)pyridine is considered to be relatively stable under normal conditions, but it should be handled and stored with caution due to its potential for causing irritation to the skin, eyes, and respiratory system.

InChI:InChI=1/C13H11N/c1-2-6-12(7-3-1)9-10-13-8-4-5-11-14-13/h1-11H/b10-9+

Upstream product

• 109-06-8 α-picoline 
• 100-52-7 benzaldehyde 
• 1121-60-4 pyridine-2-carbaldehyde 
• 109-09-1 2-chloropyridine 
• 100-42-5 styrene 
• 2294-74-8 1-phenyl-2-pyridin-2-yl-ethanol 
• 109-04-6 2-bromo-pyridine 
• 100-69-6 2-vinylpyridine 
• 108-86-1 bromobenzene 
• 5029-67-4 2-iodopyridine 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 591-50-4 iodobenzene 
• 110-86-1 pyridine 
• 6738-06-3 phenylethynylmagnesium bromide 

Downstream Products

• 1121-60-4 pyridine-2-carbaldehyde 
• 13474-48-1 1-phenyl-2-pyridin-2-yl-ethane-1,2-dione 
• 17152-06-6 2-(benzo[b]selenophen-2-yl)pyridine 
• 132363-97-4 2-(2-phenylethyl)piperidine 
• 17254-22-7 (+/-)-6-trans-styryl-9aH-quinolizin-1,2,3,4-tetracarboxylic acid tetramethyl ester 
• 1718-64-5 1-methyl-2-styrylpyridinium iodide 
• 87922-24-5 meso-1,2-dibromo1-(2-pyridyl)-2-phenylethane 
• 22172-84-5 2-(2-phenylethyl)tetrahydro-2H-pyran 
• 97026-56-7 2-(1-chloro-2-phenyl-ethyl)-pyridine 
• 6294-62-8 2-stilbazole dibromide 
• 2116-62-3 2-(2-phenylethyl)pyridine 
• 35469-61-5 (E)-2-(α-styryl)pyridine 1-oxide 
• 70779-18-9 6-benzhydryl-3,3,4-triphenyl-5-pyridin-2-yl-3,4-dihydro-pyran-2-one 
• 60601-60-7 2-(2-cyclohexylethyl)-piperidine hydrochloride 

Relevant articles and documents

X-ray crystal structure of 2-styrylpyridine

We have crystallized the 2-styrylpyridine from the condensation reaction between the 2-methylpyridine with benzaldehyde in the formation of the model compound 2-styrylpyridine. The X-ray structure and NMR are currently reported. The main features of the structure is that it shows a localization of the double bonds rather than a delocalization of π electrons in an aromatic fashion.

A new insight into the push-pull effect of substituents via the stilbene-like model compounds

In this paper, authors report on 1-pyridyl-2-arylethenes, 1-furyl-2-arylethylenes, 1,2-diphenylpropylenes and substituted cinnamyl anilines as stilbene-like model compounds to investigate the factors dominating the push-pull effect of substituents via usi

Copper(0) nanoparticle catalyzed Z-Selective Transfer Semihydrogenation of Internal Alkynes

The use of copper(0) nanoparticles in the transfer semihydrogenation of alkynes has been investigated as a lead-free alternative to Lindlar catalysts. A stereo-selective methodology for the hydrogenation of internal alkynes to the corresponding (Z)-alkenes in high isolated yields (86% average) has been developed. This green and sustainable transfer hydrogenation protocol relies on non-noble copper nanoparticles for reduction of both electron-rich and electron-deficient, aliphatic-substituted and aromatic- substituted internal alkynes. Polyols, such as ethylene glycol and glycerol, have been proven to act as hydrogen sources, and excellent stereo- and chemoselectivity have been observed. Enabling technologies, such as microwave and ultrasound irradiation are shown to enhance heat and mass transfer, whether used alone or in combination, resulting in a decrease in reaction time from hours to minutes. (Figure presented.).