54088-56-1

Usage

Urea derivative

1-tert-butyl-3-cyclohexylurea is a compound derived from urea, which means it has a similar structure to urea with some modifications.

tert-Butyl group

A tert-butyl group (C4H9) is attached to the urea molecule, contributing to the compound's structure and properties.

Cyclohexyl group

A cyclohexyl group (C6H11) is also attached to the urea molecule, providing a cyclic structure and additional properties to the compound.

Organic chemical compound

1-tert-butyl-3-cyclohexylurea is an organic compound, meaning it is primarily composed of carbon, hydrogen, and other non-metal elements.

Use as a catalyst

In organic synthesis, 1-tert-butyl-3-cyclohexylurea is commonly used as a catalyst to speed up chemical reactions and increase the yield of desired products.

Use as a reagent

The compound is also used as a reagent in various chemical reactions, facilitating the formation of new bonds or the transformation of reactants into products.

Applications in pharmaceuticals

1-tert-butyl-3-cyclohexylurea has a wide range of applications in the pharmaceutical industry, including the synthesis of drugs and the development of new therapeutic agents.

Applications in agriculture

The compound is also used in agriculture, potentially for the development of pesticides, herbicides, or other agrochemicals.

Applications in materials science

1-tert-butyl-3-cyclohexylurea can be used in the development of new materials, such as polymers, coatings, or other advanced materials with unique properties.

Unique structure and properties

The combination of the tert-butyl and cyclohexyl groups, along with the urea core, gives 1-tert-butyl-3-cyclohexylurea a unique structure that contributes to its versatility and value in various chemical processes.

Upstream product

• 1202-53-5 t-butylcyclohexylcarbodiimide 
• 1122-56-1 cyclohexylcarboxamide 
• 75-64-9 tert-butylamine 
• 13810-02-1 N-hydroxycyclohexanecarboxamide 
• 108-91-8 cyclohexylamine 
• 4421-48-1 N-cyanocyclohexylamine 
• 75-65-0 tert-butyl alcohol 
• 92109-08-5 cyclohexylcarbamic acid 4-nitrophenyl ester 

Downstream Products

• 22394-78-1 N¹--N²-cyclohexyl-formamidin 

Relevant academic research and scientific papers

An easy access to unsymmetrical ureas: A photocatalytic approach to the Lossen rearrangement

An efficient and operationally simple method for the synthesis of unsymmetrical ureas from various hydroxamic acids and amines has been developed. Plausibly, the protocol involves visible-light-initiated in situ formation of Vilsmeier-Haack reagent and COBr2 with CBr4 and a catalytic amount of DMF in the presence of Ru(bpy)3Cl2 as a photocatalyst to bring about the Lossen rearrangement at room temperature. the Partner Organisations 2014.

Iron(III) catalysed synthesis of unsymmetrical di and trisubstituted ureas - A variation of classical Ritter reaction

An application of the classical Ritter reaction for the synthesis of unsymmetrical di and trisubstituted ureas catalyzed by FeCl3 is described. The protocol is of significant interest in view of the easy availability of precursors, mild reaction conditions employed and interestingly its applicability for the alkylation of alcohols capable of forming stable carbocationic intermediates even to the sterically hindered moieties. The Royal Society of Chemistry 2012.

The efficient synthesis of carbodiimides using a titanium imido complex

An efficient rt synthesis of carbodiimides or ureas from the combination of a titanium imido complex 2 and a range of 12 aryl and aliphatic isocyanates is described. Control experiments suggest that carbodimide formation is via heterocumulene metathesis t

A New Convenient Method for the Synthesis of Symmetrical and Unsymmetrical N,N'-Disubstituted Ureas

A new method is described for the preparation of symmetrically and unsymmetrically disubstituted ureas by aminolysis of bis(4-nitrophenyl) carbonate.The second substitution is slower than the first one, and it is possible to isolate monosubstituted intermediates when equimolar amounts of substrates are used.The reaction of the intermediates with different amines give unsymmetrical derivatives of urea.