54147-92-1Relevant academic research and scientific papers
Iron-Catalyzed Aerobic Dehydrogenative Kinetic Resolution of Cyclic Secondary Amines
Lu, Ran,Cao, Liya,Guan, Honghao,Liu, Lei
supporting information, p. 6318 - 6324 (2019/05/09)
A nonenzymatic iron-catalyzed dehydrogenative kinetic resolution of cyclic secondary amines using air as an oxidant has been reported. The economical and practical method is applicable to a series of cyclic benzylic amines, including 5,6-dihydrophenanthridines and 1,2-dihydroquinolines, with diverse functional groups at the α position in high yields with excellent enantioselectivities. The direct dehydrogenative kinetic resolution of advanced intermediates of bioactive molecules that are difficult to access using existing catalytic asymmetric synthetic strategy was also demonstrated.
Efficient synthesis of phenanthridines using Hendrickson reagent initiated cascade reaction under mild conditions
Xi, Jie,Dong, Qing-Li,Liu, Guan-Sai,Wang, Shaozhong,Chen, Lin,Yao, Zhu-Jun
supporting information; experimental part, p. 1674 - 1678 (2010/08/20)
A number of variously substituted phenanthridines have been synthesized using the newly developed methodology under mild conditions. The Hendrickson reagent initiated cascade annulation, which is composed of a mild conversion of stable amide precursor to highly reactive imido-carbonium intermediate and a subsequent intramolecular Friedel-Crafts reaction, successfully served as the key method. Georg Thieme Verlag Stuttgart New York.
Iron-catalyzed aryl-aryl cross-coupling reaction tolerating amides and unprotected quinolinones
Kofink, Christiane C.,Blank, Benoit,Pagano, Sandro,Goetz, Nadine,Knochel, Paul
, p. 1954 - 1956 (2008/02/07)
The iron(III)-catalyzed cross-coupling reaction between functionalized arylcopper reagents and aromatic iodides bearing an amide function or an unprotected quinolinone leads smoothly to polyfunctionalized biphenyls in excellent yields due to an intramolec
Application of Semmler-Wolff Reaction for the Synthesis of 2-Aminobiphenyls
Sivasubramanian, S.,Muthusubramanian, S.,Ramasamy, S.,Arumugam, N
, p. 552 - 554 (2007/10/02)
Semmler-Wolff reaction of 1-hydroxyimino-2-aryl-2-cyclohexenes (I) yields the corresponding 2-aminobiphenyls (II) in 40-55percent yield.The 2-aminobiphenyls have been fully characterized through spectral data.Further confirmation of the structures of 2-aminobiphenyls is obtained by their conversion to the corresponding phenanthridine derivatives (IV).
