5418-07-5

Basic information

• Product Name: 2-aMino-4,6-diphenyl-s-trizine
• Synonyms: 2-aMino-4,6-diphenyl-s-trizine;2-Amino-4,6-diphenyl-1,3,5-triazine;NSC 11699;4,6-diphenyl-[1,3,5]triazin-2-ylamine
• CAS NO: 5418-07-5
• Molecular Formula: C₁₅H₁₂N₄
• Molecular Weight: 248.28258
• Mol File: 5418-07-5.mol

Chemical Properties

• Melting Point: 173-174℃ (heptane )
• Boiling Point: 510.1°C at 760 mmHg
• Flash Point: 294.9°C
• Appearance: /
• Density: 1.229g/cm³
• Vapor Pressure: 1.6E-10mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: 2-aMino-4,6-diphenyl-s-trizine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aMino-4,6-diphenyl-s-trizine(5418-07-5)
• EPA Substance Registry System: 2-aMino-4,6-diphenyl-s-trizine(5418-07-5)

Safety Data

• Hazardous Substances Data: 5418-07-5(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis Industry:
2-Amino-4,6-diphenyl-s-triazine is used as an intermediate in the synthesis of various dyes, pharmaceuticals, and other organic compounds. Its unique chemical structure allows it to be a key component in creating a wide range of products.
Used in Nitrocellulose Production:
In the manufacturing process of nitrocellulose, 2-Amino-4,6-diphenyl-s-triazine is utilized as a stabilizer. This helps to prevent the degradation of nitrocellulose, ensuring the quality and performance of the final product.
Used in Rubber and Plastics Industry:
2-aMino-4,6-diphenyl-s-trizine is also employed in the production of rubber and plastics, where it acts as a stabilizer. This contributes to the durability and longevity of rubber and plastic products, enhancing their overall performance.
Used in Medical Applications:
2-Amino-4,6-diphenyl-s-triazine has shown promise in the medical field, particularly as an anti-inflammatory and anti-cancer agent. Its potential therapeutic effects are currently being explored, with the aim of developing new treatments for various conditions.

InChI:InChI=1/C15H12N4/c16-15-18-13(11-7-3-1-4-8-11)17-14(19-15)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19)

Upstream product

• 72428-36-5 3-chloro-5-phenyl-1,2,4-triazine 
• 933-20-0 4,6-dichloro-1,3,5-triazin-2-amine 
• 71-43-2 benzene 
• 24108-43-8 3,5-diphenyl-1,2,4-triazine 
• 72428-38-7 3-iodo-5-phenyl-1,2,4-triazine 
• 72428-37-6 3-bromo-5-phenyl-1,2,4-triazine 
• 50-01-1 guanidine hydrochloride 
• 99910-32-4 (E)-1-methylthio-1,3-diphenyl-2-azabuta-1,3-diene-4,4-dicarbonitrile 
• 1898-74-4 2,4-diphenyl-1,3,5-triazine 
• 113-00-8 guanidine nitrate 
• 100-47-0 benzonitrile 
• 3842-55-5 2-chloro-4,6-diphenyl-1,3,5-triazine 
• 98-80-6 phenylboronic acid 

Downstream Products

• 33957-63-0 4-amino-6-phenyl-1H-[1,3,5]triazin-2-one 
• 111337-16-7 (4,6-diphenyl-[1,3,5]triazin-2-yl)-urea 

Relevant articles and documents

METHOD FOR PRODUCING 2-AMINO-1,3,5-TRIAZINE COMPOUND

PROBLEM TO BE SOLVED: To provide a method for producing 2-amino-4,6-di-substituted 1,3,5-triazine simply and under a mild condition. SOLUTION: Guanidine or a salt thereof is added to a mixture including a nitrile compound and a base and reacted therewith to produce 2-amino-4,6-di-substituted 1,3,5-triazine. Alternatively, a mixture (or a mixed liquid) including guanidine or a salt thereof and a solvent may be added to a mixture (or a mixed liquid) including a nitrile compound, a base and a solvent and reacted therewith. The base may be an alkali metal hydride, for example, sodium hydride. After completing the reaction, a step of depositing a deposit by adding a poor solvent to the reaction mixture and a step of separating the deposited deposit may be included. SELECTED DRAWING: None COPYRIGHT: (C)2021,JPOandINPIT

A PROCESS FOR THE PREPARATION OF UV ABSORBERS

The presently claimed invention relates to a novel, highly efficient and general process for the preparation of UV absorbers.

Organic optoelectronic material and application thereof

The invention belongs to the scientific and technical field of optoelectronic material application, and particularly relates to an organic photoelectric material and application thereof. The organic photoelectric material comprises phenanthroimidazole and

SYNTHESIS OF NITROGEN HETEROCYCLES FROM 1-METHYLTHIO-2-PHENYL-2-AZABUTA-1,3-DIENE-4,4-DICARBONITRILES

The reactions of title compounds with different nucleophiles afforded a simple method for a synthesis of pyrimidines, 1,2,4-triazoles, 1,2,4-oxadiazoles and 1,3,5-triazines.

A potassium amide induced ring transformation of 1,2,4-triazines into 1,2,4-triazoles and 1,3,5-triazines

5-Phenyl- and 3,5-diphenyl-1,2,4-triazine, when treated with potassium amide in liquid ammonia, are converted into a mixture of phenyl derivatives of 1,2,4-triazole and amino-1,3,5-triazines. The ring contraction of the 1,2,4-triazine ring into the 1,2,4-triazole ring has been explained by an initial addition of the amide ion to C-6, ring opening by fission of the N1-C6 bond and ring closure (ANRORC-mechanism). The transformation of the 1,2,4-triazine ring into the 1,3,5-triazine ring has been studied by means of 15N-labeled potassium amide. It was found that the nitrogen of the amide ion becomes one of the ring nitrogen atoms in the 1,3,5-triazine ring and that the exocyclic amino group is imlabeled. Based on these 15N-labeling studies, it is proposed that this ring transformation starts with an initial addition of the amide ion to C-5, ring opening between C-5 and C-6, a dehydrogenative rearrangement of the open-chain intermediate 1-amino-2,4,5-triazahexatriene into 1-amino-4-cyano-2,4-diaza-1,3-butadiene, and ring closure.

On the Amination of Azaheterocycles. A New Procedure for the Introduction of an Amino Group

A new method of amination of diazines and triazines, using potassium amide, liquid ammonia and potassium permanganate, has been described.

Ring Transformations and Amination in Reactions of 3-Halogeno-5-phenyl-1,2,4-triazines with Potassium Amide in Liquid Ammonia

The reactions of 3-X-5-phenyl-1,2,4-triazines (X = fluoro, chloro, bromo, iodo) toward potassium amide/liquid ammonia were studied.Whereas the 3-fluoro compound gives only the 3-amino derivative, the 3-chloro, 3-bromo, and 3-iodo compounds yield a complex mixture containing, besides 3-amino-5-phenyl-1,2,4-triazine and 5-phenyl-1,2,4-triazine, ring transformation products, i.e., 3,5-diphenyl-1,2,4-triazine, 2,4-diphenyl-1,3,5-triazine, 6-amino-2,4-diphenyl-1,3,5-triazine, and 3-X-5-phenyl-1,2,4-triazole.Evidence is found that in the ring transformation of 3-X-5-phenyl-1,2,4-triazines into 2,4-diphenyl-1,3,5-triazines, benzamidine must be an intermediate.The mechanisms of the amination and ring transformation are extensively discussed.