3842-55-5

Usage

Uses

Used in Research Chemicals:
2-chloro-4,6-diphenyl-1,3,5-triazine is used as a research chemical, providing a foundation for scientific investigations and the development of new chemical processes and applications.
Used in Organic Synthesis:
Used in Organic Light Emitting Diodes (OLEDs):
2-chloro-4,6-diphenyl-1,3,5-triazine is used as a precursor to prepare benzimidazole compounds and derivatives, which are essential in the development of organic electron transport materials. These materials have significant applications in OLEDs, contributing to the advancement of new electroluminescent displays and lighting technologies.
Used in Organic Small Molecule Electron Transport Materials:
Furthermore, 2-chloro-4,6-diphenyl-1,3,5-triazine is utilized in the preparation of organic small molecule electron transport materials, which are crucial for enhancing the performance and efficiency of electronic devices and systems.

Synthesis Reference(s)

The Journal of Organic Chemistry, 34, p. 4125, 1969 DOI: 10.1021/jo01264a079Synthesis, p. 841, 1980 DOI: 10.1055/s-1980-29230

InChI:InChI=1/C15H10ClN3/c16-15-18-13(11-7-3-1-4-8-11)17-14(19-15)12-9-5-2-6-10-12/h1-10H

Synthetic route

1,3,5-trichloro-2,4,6-triazine (108-77-0) + phenylboronic acid (98-80-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With bis(tricyclohexylphosphine)nickel(II) dichloride; potassium carbonate In tetrahydrofuran at 70℃; for 12h; Reagent/catalyst; Solvent; Temperature; Friedel-Crafts Alkylation; Green chemistry;	94.1%
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In water; toluene for 8h; Inert atmosphere; Reflux;	71%
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; toluene for 8h; Inert atmosphere; Reflux;	71%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + benzene (71-43-2) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With aluminum (III) chloride In 5,5-dimethyl-1,3-cyclohexadiene at 70℃; for 4h; Time; Temperature;	92%
With hydrogenchloride; aluminum (III) chloride In water; chlorobenzene at 20℃; for 25h; Temperature; Reagent/catalyst; Cooling with ice;	84%
With aluminum (III) chloride In ethyl acetate; chlorobenzene at 18 - 22℃; for 4h;

1,3,5-trichloro-2,4,6-triazine (108-77-0) + phenylmagnesium bromide (100-58-3) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
In tetrahydrofuran at 0 - 20℃; for 12h; Inert atmosphere;	89%
In tetrahydrofuran at 0 - 20℃; for 12h;	80%
In tetrahydrofuran; diethyl ether at 0 - 20℃; for 13h;	80.5%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole (24388-23-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With potassium phosphate; palladium diacetate In water; N,N-dimethyl-formamide at 130℃; for 10h; Inert atmosphere;	85.2%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃;	64%

2,4-dichloro-6-phenyl-1,3,5-triazine (1700-02-3) + phenylboronic acid (98-80-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 10h; Inert atmosphere;	75.4%
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate In water; toluene for 10h; Inert atmosphere; Reflux;	75%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 10h; Inert atmosphere;	67.3%

4,6-diphenyl-1H-[1,3,5]triazin-2-one (1917-44-8) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With N,N-diethylaniline; trichlorophosphate at 140℃; for 6h; Sealed tube;	74%
With thionyl chloride; phosphorus pentachloride; 1,2-dichloro-benzene at 140℃;

bromobenzene (108-86-1) + 1,3,5-trichloro-2,4,6-triazine (108-77-0) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
Stage #1: bromobenzene With iodine; magnesium In tetrahydrofuran for 4h; Inert atmosphere; Reflux; Stage #2: 1,3,5-trichloro-2,4,6-triazine In tetrahydrofuran for 5h; Inert atmosphere;	73.5%
Stage #1: bromobenzene With iodine; magnesium In tetrahydrofuran for 1h; Inert atmosphere; Reflux; Stage #2: 1,3,5-trichloro-2,4,6-triazine In tetrahydrofuran for 7h; Reflux; Inert atmosphere;	73.5%
Stage #1: bromobenzene With magnesium In tetrahydrofuran at 40 - 50℃; Stage #2: 1,3,5-trichloro-2,4,6-triazine In tetrahydrofuran at -5 - 5℃;	72.8%

2,4-dichloro-6-phenyl-1,3,5-triazine (1700-02-3) + 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole (24388-23-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); sodium hydroxide In tetrahydrofuran; water Reflux;	66%

2,4,6-trichloropyrimidine (3764-01-0) + 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole (24388-23-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 90℃;	65%

2,4,6-trichloropyrimidine (3764-01-0) + phenylmagnesium bromide (100-58-3) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
In tetrahydrofuran at 0 - 50℃; for 10h;	61%

N-phenyl benzoyl amide (93-98-1) + N′-cyanobenzamidine (17513-09-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + (4,6-Diphenyl-1,3,5-triazin-2-yl)phenylamine (30369-20-1)

Conditions	Yield
With phosphorus pentachloride CH3CN, 1h, reflux; Yield given. Multistep reaction;	A 48% B n/a
With phosphorus pentachloride CH3CN, 1h, reflux; Yield given. Multistep reaction;	A n/a B 25%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + phenylmagnesium bromide → 2,4-dichloro-6-phenyl-1,3,5-triazine (1700-02-3) + 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With diethyl ether

1,3,5-trichloro-2,4,6-triazine (108-77-0) + phenylmagnesium bromide → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

5-nitroso-2,4-diphenyl-imidazole (95390-15-1) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With chloroform; phosphorus pentachloride

N′-cyanobenzamidine (17513-09-6) + 4-(Chloro-phenyl-methylene)-morpholin-4-ium; chloride → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
In toluene for 1h; Heating; Yield given;

N′-cyanobenzamidine (17513-09-6) + N,N-dimethylbenzamide (611-74-5) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With trichlorophosphate 1.) 5 min, 100 deg C, 2.) CH3CN, 30 min, reflux; Yield given. Multistep reaction;

chloroform (67-66-3) + 5-nitroso-2,4-diphenyl-imidazole (95390-15-1) + phosphorus pentachloride (10026-13-8, 874483-75-7) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

6-oxy-2.4-diphenyl-1.3.5-triazine → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With trichlorophosphate

bromobenzene (108-86-1) + 1,3,5-trichloro-2,4,6-triazine (108-77-0) + iodine-activated magnesium → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
With hydrogenchloride In tetrahydrofuran; water; toluene
With hydrogenchloride In tetrahydrofuran; water; chlorobenzene; toluene

2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole (24388-23-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0); sodium hydroxide / tetrahydrofuran; water / Reflux 2: tetrakis(triphenylphosphine) palladium(0); sodium hydroxide / tetrahydrofuran; water / Reflux View Scheme

1,3,5-trichloro-2,4,6-triazine (108-77-0) + phenylmagnesium chloride (100-59-4) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
In tetrahydrofuran at 0 - 20℃; for 15h;	42.8 g

phenylboronic acid (98-80-6) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / tetrahydrofuran; water / 10 h / 80 °C 2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / tetrahydrofuran; water / 10 h / 80 °C / Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / tetrahydrofuran; water / 10 h / 80 °C / Inert atmosphere 2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / tetrahydrofuran; water / 10 h / 80 °C / Inert atmosphere View Scheme
Multi-step reaction with 2 steps 1: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / toluene / 10 h / Inert atmosphere; Reflux 2: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / toluene; water / 10 h / Inert atmosphere; Reflux View Scheme

isocyanuric acid (108-80-5) + benzene (71-43-2) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
Stage #1: isocyanuric acid; benzene With 1-butyl-3-methylimidazolium Tetrafluoroborate In 1,2-dichloro-benzene at 5℃; for 2h; Stage #2: With hydrogenchloride In 1,2-dichloro-benzene at 5 - 15℃; for 12h; Reagent/catalyst;

bromobenzene (108-86-1) → 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5)

Conditions	Yield
Multi-step reaction with 2 steps 1: pd catalyst / tetrahydrofuran / 5 h / 80 °C / Inert atmosphere 2: potassium phosphate; palladium diacetate / water; N,N-dimethyl-formamide / 10 h / 130 °C / Inert atmosphere View Scheme

4-amino-3-nitrophenylboronic acid pinacol ester (833486-94-5) + 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) → C21H15N5O2

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water; toluene for 12h; Reflux;	100%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 5,8-dihydro-indolo[2,3-C]carbazole → C48H30N8

Conditions	Yield
Stage #1: 5,8-dihydro-indolo[2,3-C]carbazole With sodium hydride In N,N-dimethyl-formamide for 1h; Inert atmosphere; Stage #2: 2-chloro-4,6-diphenyl-1,3,5-triazine In N,N-dimethyl acetamide Inert atmosphere;	100%
With tetrakis(triphenylphosphine) palladium(0); sodium hydroxide In water Reflux; Inert atmosphere;

3-bromo-9H-carbazole (1592-95-6) + 2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) → 3-bromo-9-(4,6-diphenyl-[1,3,5]triazin-2-yl)-9H-carbazole (1266389-17-6)

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 12h; Inert atmosphere;	98%
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 8h; Inert atmosphere;	93.2%
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 16h; Inert atmosphere;	90%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 4-Bromophenylboronic acid (5467-74-3) → 2-(4-bromobenzenyl)-4,6-diphenyl-1,3,5-triazine (23449-08-3)

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 12h; Inert atmosphere;	96%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water; toluene for 12h; Reflux;	96.5%
With tetrakis(triphenylphosphine) palladium(0); tetrabutyl-ammonium chloride; potassium carbonate In ethanol; water; toluene at 78℃; for 10h; Inert atmosphere;	82%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C42H37BO2 → C51H35N3

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran at 80℃; for 20h; Inert atmosphere;	96%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 2,6-dichlorophenylboronic acid (73852-17-2) → 2-(2,6-dichlorophenyl)-4,6-diphenyl-1,3,5-triazine

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; water for 12h; Reflux; Inert atmosphere;	96%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) → 2-chloro-4,6-bis(phenyl-D5)-1,3,5-triazine

Conditions	Yield
With platinum(IV) oxide; water-d2 at 250℃; for 14h;	96%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 4-fluoroboronic acid (1765-93-1) → 2-di(4-fluorophenyl)-4,6-diphenyl-1,3,5-triazine

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at -20℃; Suzuki Coupling; Reflux;	95.3%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 10h; Inert atmosphere; Reflux;	93%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran for 10h; Inert atmosphere; Reflux;	93%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + anthracene-9-boronic acid (100622-34-2) → 2-(9-anthryl)-4,6-diphenyl-1,3,5-triazine

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; water; toluene at 90℃; for 12h;	95%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In ethanol; toluene at 110℃; for 12h; Inert atmosphere;	95.17%
Stage #1: 2-chloro-4,6-diphenyl-1,3,5-triazine; anthracene-9-boronic acid With tetrakis(triphenylphosphine) palladium(0) In ethanol; toluene for 0.5h; Inert atmosphere; Stage #2: With sodium carbonate In ethanol; toluene at 80℃; for 12h; Inert atmosphere;	70%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C33H31BO3 → C42H29N3O

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 8h; Inert atmosphere;	95%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + (3-bromophenyl)boronic acid (89598-96-9) → 2-(3-bromo-phenyl)-4,6-diphenyl-1,3,5-triazine (864377-31-1)

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 12h; Inert atmosphere;	95%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 12h; Inert atmosphere;	95%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water at 80℃; for 12h; Inert atmosphere;	95%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 7-bromo-12,12-dimethyl-10,12-dihydro-10-azaindeno[2,1-b]fluorene (1257247-97-4) → 2-bromo-5- (4,6-diphenyl-1,3,5-triazin-2-yl)-7,7-dimethyl-5,7-dihydroindeno[2,1-b]carbazole (1257247-98-5)

Conditions	Yield
Stage #1: 7-bromo-12,12-dimethyl-10,12-dihydro-10-azaindeno[2,1-b]fluorene With sodium hydride In N,N-dimethyl-formamide; mineral oil at 20℃; for 1h; Stage #2: 2-chloro-4,6-diphenyl-1,3,5-triazine In N,N-dimethyl-formamide; mineral oil at 20℃; for 12h;	95%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C24H15N → C39H24N4

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene at 110℃; for 15h; Inert atmosphere;	95%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C25H18N2 → C40H27N5

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene for 3h; Reflux;	95%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 2,2'-(4-fluoro-1,3-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) → 6,6'-(4-fluoro-1,3-phenylene)bis(2,4-diphenyl-1,3,5-triazine)

Conditions	Yield
With potassium phosphate; tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; water at 100℃; for 16h; Suzuki Coupling; Inert atmosphere;	95%
With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; water at 100℃; for 16h; Inert atmosphere;

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C29H20N2 → C44H29N5

Conditions	Yield
With tris-(dibenzylideneacetone)dipalladium(0); tri-tert-butyl phosphine; sodium t-butanolate In toluene at 100℃; for 3h;	95%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 2-(6-(9,9-dimethyl-9H-xanthen-3-yl)dibenzo[b,d]furan-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → C42H29N3O2

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In 1,4-dioxane; water at 120℃; for 3h;	95%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 3,4,5-trifluorophenylboronic acid (143418-49-9) → 2, 4-diphenyl-6-(3,4,5-trifluorophenyl)-1,3,5-triazine

Conditions	Yield
Stage #1: 2-chloro-4,6-diphenyl-1,3,5-triazine; 3,4,5-trifluorophenylboronic acid With potassium carbonate In tetrahydrofuran; water at 20℃; Inert atmosphere; Stage #2: With tetrakis(triphenylphosphine) palladium(0) In tetrahydrofuran; water for 12h; Reflux;	94%
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In ethanol; water; toluene at 106℃; for 12h; Suzuki-Miyaura Coupling; Inert atmosphere;	77%
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In water; trifluoroacetic acid
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C33H30BNO3 → C42H28N4O

Conditions	Yield
With tetrakis(triphenylphosphine) palladium(0); potassium carbonate In tetrahydrofuran; water for 4.5h; Inert atmosphere; Heating;	94%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 3-chloro-4-fluorophenylboronic acid (144432-85-9) → 2-(3-chloro-4-fluorophenyl)-4,6-diphenyl-1,3,5-triazine

Conditions	Yield
With palladium diacetate; sodium carbonate; tris-(o-tolyl)phosphine In tetrahydrofuran; water for 2h; Inert atmosphere; Reflux;	94%
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In water; toluene Reflux;	82%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 3-bromo-9H-carbazole sodium salt → 3-bromo-9-(4,6-diphenyl-[1,3,5]triazin-2-yl)-9H-carbazole (1266389-17-6)

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide	94%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + 3-(dibenzo[b,d]furan-4-yl)-9H-carbazole (1346669-46-2) → 3-(dibenzo[b,d]furan-4-yl)-9-(4,6-diphenyl-1,3,5-triazin-2-yl)-9H-carbazole (1346669-12-2)

Conditions	Yield
Stage #1: 3-(dibenzo[b,d]furan-4-yl)-9H-carbazole With sodium hydride In N,N-dimethyl-formamide for 0.25h; Inert atmosphere; Stage #2: 2-chloro-4,6-diphenyl-1,3,5-triazine In N,N-dimethyl-formamide at 20℃; Inert atmosphere;	93.5%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C28H17NO → C43H26N4O

Conditions	Yield
Stage #1: C28H17NO With sodium hydride In N,N-dimethyl-formamide for 0.25h; Inert atmosphere; Stage #2: 2-chloro-4,6-diphenyl-1,3,5-triazine In N,N-dimethyl-formamide for 2h;	93.5%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + sodium methylate (124-41-4) → 2-methoxy-4,6-diphenyl-1,3,5-triazine (108718-58-7)

Conditions	Yield
In methanol for 0.5h; Ambient temperature;	93%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C18H11NO2 → C33H20N4O2

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h;	93%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C26H16N2 → C41H25N5

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;	93%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C30H20N2 → C45H29N5

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;	93%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C24H16N2 → C39H25N5

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;	93%

2-chloro-4,6-diphenyl-1,3,5-triazine (3842-55-5) + C24H16N2 → C39H25N5

Conditions	Yield
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 1h; Inert atmosphere;	93%

Upstream product

• 108-77-0 1,3,5-trichloro-2,4,6-triazine 
• 95390-15-1 5-nitroso-2,4-diphenyl-imidazole 
• 1917-44-8 4,6-diphenyl-1H-[1,3,5]triazin-2-one 
• 93-98-1 N-phenyl benzoyl amide 
• 17513-09-6 N′-cyanobenzamidine 
• 611-74-5 N,N-dimethylbenzamide 
• 67-66-3 chloroform 
• 10026-13-8 phosphorus pentachloride 
• 108-86-1 bromobenzene 
• 98-80-6 phenylboronic acid 
• 71-43-2 benzene 
• 3764-01-0 2,4,6-trichloropyrimidine 
• 100-58-3 phenylmagnesium bromide 
• 108-80-5 isocyanuric acid 

Downstream Products

• 493-77-6 2,4,6-triphenyl-1,3,5-triazine 
• 30369-20-1 (4,6-Diphenyl-1,3,5-triazin-2-yl)phenylamine 
• 1917-44-8 4,6-diphenyl-1H-[1,3,5]triazin-2-one 
• 30886-16-9 4,6-diphenyl-1H-[1,3,5]triazine-2-thione 
• 1493-45-4 2-fluoro-4,6-diphenyl-1,3,5-triazine 
• 5418-07-5 4,6-diphenyl-[1,3,5]triazin-2-ylamine 
• 80465-20-9 2-Ethoxy-4,6-diphenyl-1,3,5-triazin 
• 68265-99-6 4,6-diphenyl-1,3,5-triazine-2-carbonitrile 
• 108718-58-7 2-methoxy-4,6-diphenyl-1,3,5-triazine 
• 113696-91-6 α-phenyl-4,6-diphenyl-s-triazine-2-acetonitrile 
• 113696-94-9 2-benzoyl-4,6-diphenyl-s-triazine 
• 122195-35-1 2-(4-Chlor-phenoxy)-4,6-diphenyl-1,3,5-triazin 
• 122977-83-7 2-<1-(4-Chlor-phenoxy)-3-phenoxy-prop-2-oxy>-4,6-diphenyl-1,3,5-triazin 
• 113696-93-8 2-phenacyl-4,6-diphenyl-s-triazine 

Relevant academic research and scientific papers

COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF

The present invention relates to high luminous efficiency of a device. The present invention provides a compound capable of improving a low driving voltage and a lifespan, an organic electronic element using the same, and an electronic device thereof.

Polymerizable UV absorbers for the UV stabilization of polyesters. I. Design, synthesis and polymerization of a library of UV absorbing monomers

UV stabilizers, such as Tinuvin 1577, are organic additives that are used in the polymer industry to suppress polymer photodegradation, however leaching of the stabilizers from polymers is a significant practical issue which limits the effectiveness of the stabilizers and restricts polymer lifetimes. Novel, polymerizable UV stabilizers were synthesised and copolymerized with bis(2-hydroxyethyl) isophthalate to yield poly(ethylene isophthalate) copolymers where the UV stabilizers are bound covalently into the polymer chains. This strategy prevents leaching of stabilizers from polymers over time, and is expected to lead to enhanced UV protection of polymers compared to the admixing of polymers with UV stabilizers of low molar mass.

Aromatic compound and organoelectroluminescent device comprising the compound

The present invention relates to an aromatic compound and an organic electroluminescent device including the same. The aromatic compound is represented by chemical formula 1, and the organic electroluminescent device is excellent in driving voltage, luminous efficiency and lifetime characteristics.

Efficient Hydro- and Organogelation by Minimalistic Diketopiperazines Containing a Highly Insoluble Aggregation-Induced, Blue-Shifted Emission Luminophore**

We report the synthesis, gelation abilities and aggregation-induced, blue-shifted emission (AIBSE) properties of two minimalistic diketopiperazine-based gelators. Despite containing a highly insoluble luminophore that makes up more than half of their respective molecular masses, efficient hydrogelation by multiple stimuli for one and efficient organogelation for the other compound are reported. Insights into the aggregation and gelation properties were gained through examination of the photophysical and material properties of selected gels, which are representative of the different modes of gelation. The synthesis of the gelators is highly modular and based on readily available amino acid building blocks, allowing the efficient and rapid diversification of these core structures and fine-tuning of gel properties.

Heterocyclic com pounds and organic light-emitting diode including the same

The present invention relates to a novel heterocyclic compound and an organic light emitting element including the same as a light-emitting material and, more specifically, to a heterocyclic compound having excellent light emission properties, such as a driving voltage, light emission efficiency, and service life, and an organic light emitting element including the same. Since the heterocyclic compound according to the present invention is more stable compared to conventional materials and has the excellent light emission properties for the driving voltage or current efficiency, and service life, the organic light emitting element including the same can be more stably driven in a low-voltage and light emission efficiency can be improved.

Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy

Duchenne muscular dystrophy is a fatal disease with no cure, caused by lack of the cytoskeletal protein dystrophin. Upregulation of utrophin, a dystrophin paralogue, offers a potential therapy independent of mutation type. The failure of first-in-class utrophin modulator ezutromid/SMT C1100 in Phase II clinical trials necessitates development of compounds with better efficacy, physicochemical and ADME properties and/or complementary mechanisms. We have discovered and performed a preliminary optimisation of a novel class of utrophin modulators using an improved phenotypic screen, where reporter expression is derived from the full genomic context of the utrophin promoter. We further demonstrate through target deconvolution studies, including expression analysis and chemical proteomics, that this compound series operates via a novel mechanism of action, distinct from that of ezutromid.

Preparation method of diaryl-substituted chlorotriazine OLED intermediate

The invention provides a preparation method of a diaryl-substituted chlorotriazine OLED intermediate, and the method comprises the following steps: S1, carrying out heating reaction on an aryl nitrile compound and urea in an organic solvent under the action of strong alkali, and carrying out intermolecular ring closing to form a diaryl hydroxyl triazine compound; S2, enabling the diaryl hydroxyl triazine compound obtained in the step S1 to be subjected to a reaction under the action of phosphorus oxychloride, and obtaining the diaryl chlorinated triazine compound. According to the method, the final product can be obtained only through two-step reaction, raw materials are cheap, and expensive catalysts are not needed. The method has the characteristics of low cost, few steps, high yield, few three wastes, easiness in operation, environment friendliness, suitability for industrialization and the like.

Preparation and application of novel electron acceptor material

The invention belongs to the technical field of organic electroluminescent devices, and discloses a novel electron-deficient acceptor material and an application thereof in organic electroluminescent devices. The acceptor has a structure represented by general formulas (I) and (II). In the general formulas (I) and (II), X and Y can be respectively a C atom or an N atom; R1, R2, R3, B1, B2 and B3 are respectively and independently alkyl, amino, imino, a deuterated compound, an unsubstituted or substituted five-membered aromatic ring, a six-membered aromatic ring, a fused ring, aniline, an aniline derivative, diphenylamine and a diphenylamine derivative, wherein B1, B2 and B3 can have a general formula structure described in the specifications of the invention; and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13 and R14 are respectively and independently ahydrogen atom, a deuterium atom, alkyl, a deuterated compound, an aromatic ring, a fused ring, aniline, an aniline derivative, diphenylamine and a diphenylamine derivative.

A PROCESS FOR THE PREPARATION OF UV ABSORBERS

The presently claimed invention relates to a novel, highly efficient and general process for the preparation of UV absorbers.

Organic compound based on triazine and benzimidazolone structures and application of organic compound in organic electroluminescent device

The invention relates to an organic compound based on triazine and benzimidazolone structures and an application of the organic compound in an organic electroluminescent device. The structure of the compound simultaneously contains the triazine and benzimidazolone structures, and the compound has high glass transition temperature and molecular thermal stability; the compound is low in absorption and high in refractive index in the field of visible light, and after the compound is applied to a covering layer of an OLED device, the light extraction efficiency of the OLED device can be effectively improved; the compound disclosed by the invention also has a relatively deep HOMO energy level and high electron mobility, can be used as a hole blocking or electron transport layer material of theOLED device, and can effectively block holes or energy from being transmitted from a light emitting layer to one side of an electron layer, thereby improving the recombination efficiency of the holesand electrons in the light emitting layer, improving the light emitting efficiency of the OLED device, and prolonging the service life of the OLED device.