54186-68-4

Usage

Uses

Used in Pharmaceutical Industry:
2,2-dimethyl-5-nitro-1,3-benzodioxole serves as a synthetic intermediate, playing a crucial role in the development and production of pharmaceuticals. Its reactivity and structural features make it a valuable component in the creation of new medicinal compounds.
Used in Fragrance Industry:
In the fragrance industry, 2,2-dimethyl-5-nitro-1,3-benzodioxole is utilized as a synthetic intermediate. Its unique chemical properties allow it to contribute to the formation of various scent profiles, enhancing the complexity and richness of fragrances.
Used in Dye Industry:
2,2-dimethyl-5-nitro-1,3-benzodioxole is also employed in the dye industry, where it acts as a synthetic intermediate. Its involvement in the synthesis process helps in producing a range of dye colors, adding to the diversity of dyes available for various applications.
Used as a Reagent in Organic Reactions:
2,2-dimethyl-5-nitro-1,3-benzodioxole is used as a reagent in organic chemistry, facilitating a variety of chemical reactions. Its ability to undergo nitration reactions is particularly beneficial for the synthesis of other complex organic compounds, broadening its applications in research and development.
Safety Note:
It is imperative to handle 2,2-dimethyl-5-nitro-1,3-benzodioxole with care due to its potential harmful effects if ingested, inhaled, or comes into contact with the skin. Proper safety measures should be taken to mitigate any risks associated with its use.

InChI:InChI=1/C9H9NO4/c1-9(2)13-7-4-3-6(10(11)12)5-8(7)14-9/h3-5H,1-2H3

Upstream product

• 14005-14-2 2,2-dimethyl-1,3-benzodioxole 
• 872823-86-4 3-(2-hydroxy-5-nitro-phenoxy)-crotonic acid 
• 3316-09-4 1,2-dihydroxy-4-nitrobenzene 
• 67-64-1 acetone 
• 860598-63-6 (+/-)-(2-methyl-5-nitro-benzo[1,3]dioxol-2-yl)-acetic acid 
• 120-80-9 benzene-1,2-diol 

Downstream Products

• 7260-32-4 2-ethoxy-5-nitro-phenol 
• 81864-29-1 N-(2,2-dimethylbenzo[1,3]dioxol-5-yl)acetamide 
• 81864-31-5 2,2-dimethyl-6-nitro-benzo[1,3]dioxol-5-ylamine 
• 77400-30-7 1,2-dihydroxy-4,5-dinitrobenzene 
• 105780-30-1 1,2-Dinitro-4-hydroxy-5-methoxybenzene 
• 61963-88-0 N²-cyclohexyl-3-nitro-2-aminopyridine 
• 54186-71-9 2,2-dimethyl-5,6-nitro[1,3]benzodioxole 
• 3316-09-4 1,2-dihydroxy-4-nitrobenzene 
• 6324-89-6 2,2-dimethylbenzo[d][1,3]dioxol-5-ylamine 
• 636-93-1 5-nitroguaiacol 

Relevant academic research and scientific papers

Class of large ring heterocyclic compound restraining HCV and manufacturing and uses thereof

The invention relates to a class of compounds that inhibit HCV. The compounds are represented by Formula A. The invention also relates to preparation and pharmaceutical use of the compounds.

Copper Complexes of New Redox-Active 4,5-Bisguanidino-Substituted Benzodioxole Ligands: Control of the Electronic Structure by Counter-Ligands, Solvent, and Temperature

Herein, we analyze the possibility of controlling the electronic structure of mononuclear copper complexes featuring new redox-active 4,5-bisguanidino-substituted benzodioxole ligands. The nature of the guanidino groups, the anionic counter-ligands, the applied solvent (polarity), and the temperature are the parameters that decide if a CuIIcomplex with neutral ligand unit or a CuIcomplex with radical monocationic ligand unit is the adequate description. Under special conditions, a temperature-dependent equilibrium of the two valence tautomeric forms (CuII/neutral ligand and CuI/radical monocationic ligand) is achieved. Removal of a ligand-centered electron from a paramagnetic CuIIcomplex with a neutral ligand unit leads to a diamagnetic CuIcomplex with a dicationic ligand unit through a redox-induced electron-transfer (RIET) process.

HETEROCYCLIC HYDRAZIDE DERIVATIVES OF MONOCYCLIC BETA-LACTAM ANTIBIOTICS

Antibacterial activity has been found in compounds of the formula. Compounds having the formula and pharmaceutically acceptable salts thereof, wherein: A is a bond or alkylene; Q completes a 5- or 6-membered saturated or unsaturated(including aromatic) heterocyclic ring having one or two, hetero atoms in the ring selected from nitrogen sulfur or oxygen; X is attached to an available carbon atom in the heterocyclic ring and is hydrogen or oxo; Y is attached to an available carbon atom in the heterocyclic ring and is hydrogen, amino, hydroxyl, halogen, carboxamide, nitrile, or carboxyl, except that Y is not carboxyl when the bicyclic ring completed by Q is 2-quinolyl, 3-quinolyl, or quinoxalyl; and the remaining symbols are as defined in the specification

Pesticidal heterocyclic compounds

Compounds of the general formula: wherein R1 represents a hydrogen or halogen atom; R2 represents a halogen atom; R3 represents a hydrogen or halogen atom or an alkyl group; R4 and R5 each independent

Imidazole derivatives

Tricyclic imidazole derivatives of the formula STR1 wherein R1 is 2-pyridyl optionally substituted by lower alkyl or lower alkoxy, n is the integer 0 or 1, R2 is hydrogen or lower alkyl, R3 and R4, independently, are hydrogen or lower alkyl, A is a group of the formula STR2 m is the integer 2 or 3, R5, R6, R7 and R8, independently, are hydrogen or lower alkyl, and R9 is hydrogen and R10 is hydrogen or lower alkyl or R9 and R10 taken together are oxo, provided that at least one of R3 and R4 is lower alkyl when A is a group of the formula and their pharmaceutically acceptable acid addition salts. The compounds of formula I inhibit gastric acid secretion and prevent the formation of gastric ulcers.

An Improved Method for the Synthesis of 2,2-disubstituted and 2-Monosubstituted 1,3-Benzodioxoles

The reactions of catechol with ketones and aldehydes have been studied and convenient procedures have been developed for the preparation of the title compounds in high yields.These products undergo virtually quantitative nitration at position 5, thus providing a source of derivatives substituted in the benzene ring.

3-Phenyl,3H 1,2,3 triazolo[4,5-b]pyridines

3H-1,2,3-Triazolo[4,5-b]pyridines substituted in the 3-position have utility as analgesic, anti-inflammatory and anti-pyretic agents. They are prepared by diazotization of a 3-amino-2-(substitute) aminopyridine.