54267-71-9Relevant academic research and scientific papers
Synthesis of 5-alkylidene-1,3-dioxane-4,6-diones, an easily accessible family of axially chiral alkenes: Preparation in non-racemic form and platinum binding studies
Casadesus, Meritxell,Coogan, Michael P.,Ooi, Li-Ling
, p. 3822 - 3830 (2008/09/18)
A general synthetic route to 5-alkylidene-1,3-dioxane-4,6-diones, which are a family of axially chiral alkenes, is described. Conformational issues are explored and the platinum-binding properties of these species are discussed. That these alkenes exist as stable enantiomers is established by their partial kinetic resolution upon reaction with cysteine. The Royal Society of Chemistry 2006.
A one-pot synthesis of 3-amino-3-arylpropionic acids
Tan,Weaver
, p. 7449 - 7461 (2007/10/03)
3-Aminopropionic acids (β-amino acids) are biologically active compounds of interest in medicinal and pharmaceutical chemistry. Twenty-one 3-amino-3-arylpropionic acids were synthesized via a facile one-pot synthesis. In addition, a series of mechanistic studies have been performed to optimize the production of these β-amino acids. The reaction mechanism of this one-pot synthesis of β-amino acids, as well as the electronic effect of para-substitution and the influence of solvent polarity on the proposed reaction mechanism are discussed.
Knoevenagel condensation catalyzed by USY zeolite
Wang,Ma, YuDao,Zuo, BoJun
, p. 4107 - 4110 (2007/10/03)
The Knoevenagel condensation of substituted benzaldehydes with active methylene compounds was performed very efficiently by using a USY (ultrastable Y) zeolite as heterogeneous catalyst.
