5434-98-0

Usage

Uses

Used in Organic Synthesis:
2,2-dimethyl-5-phenylcyclohexane-1,3-dione is used as a reagent in organic synthesis for its ability to undergo various chemical reactions, including oxidation, reduction, and substitution. Its unique structural features make it a valuable component in the creation of new organic compounds.
Used in Pharmaceutical Industry:
2,2-dimethyl-5-phenylcyclohexane-1,3-dione is used as a potential precursor in the development of pharmaceutical compounds due to its unique structural features. Its potential applications in this industry are currently being explored by researchers.
Used in Chemical Industry:
2,2-dimethyl-5-phenylcyclohexane-1,3-dione is used as a building block in the chemical industry for the synthesis of various chemical products. Its distinct molecular structure allows for the creation of a wide range of compounds with different properties and applications.

Upstream product

• 859176-01-5 5,5-dimethyl-4,6-dioxo-2-phenyl-cyclohexane-1,3-dicarboxylic acid diethyl ester 
• 64-19-7 acetic acid 
• 67-56-1 methanol 
• 493-72-1 5-phenyl-cyclohexane-1,3-dione 
• 124-41-4 sodium methylate 
• 74-88-4 methyl iodide 
• 1353094-23-1 3,3-dimethyl-6-phenylcyclohex-5-ene-1,2,4-trione 
• 542-92-7 cyclopenta-1,3-diene 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 3160-32-5 (1E)-4-methyl-1-phenylpent-1-en-3-one 
• 65-85-0 benzoic acid 
• 18986-66-8 methyl 5-phenylcyclohexane-1,3-dione 
• 18986-68-0 2,2-Dimethyl-5-phenylcyclohex-4-en-1,3-dion 
• 18986-67-9 4-Brom-2,2-dimethyl-5-phenylcyclohexan-1,3-dion 

Downstream Products

• 130739-63-8 6-methyl-5-oxo-3-phenyl-heptanoic acid 
• 18986-67-9 4-Brom-2,2-dimethyl-5-phenylcyclohexan-1,3-dion 
• 19952-64-8 3t-phenyl-cyclopropane-1r,2c-dicarboxylic acid 
• 18986-69-1 3,6-Epidioxy-2,2-dimethyl-5-phenyl-cyclohexen-⁽⁴⁾-ol-⁽³⁾ 
• 18986-68-0 2,2-Dimethyl-5-phenylcyclohex-4-en-1,3-dion 
• 18986-72-6 2,2-Dimethyl-4-benzylcyclopent-4-en-1,3-dion 
• 18986-70-4 3,3-Dimethyl-6-phenylbicyclo<3.1.0>hexan-2,4-dion 
• 19952-66-0 (1RS,2RS,3RS)-3-Phenylcyclopropane-1,2-dicarboxylic acid 
• 1353094-23-1 3,3-dimethyl-6-phenylcyclohex-5-ene-1,2,4-trione 

Relevant academic research and scientific papers

Organofluorine chemistry: Difluoromethylene motifs spaced 1,3 to each other imparts facial polarity to a cyclohexane ring

2,2-Dimethyl-5-phenyl-1,1,3,3-tetrafluororocyclohexane has been prepared and characterised as an example of a facially polarised cyclohexane containing 1,3 related CF2 groups. The dipolar nature of the ring arises from the axial orientation of

The effect of Lewis acids on the cycloaddition of 3,3,6-Trimethylcyclohex- 5-ene-1,2,4-trione: Hydrogen transfer versus cycloaddition with cyclopentadiene

Exposure of 3,3,6-trimethylcyclohex-5-ene-1,2,4-trione to catalytic amounts of Lewis acids revealed two disparate reactions in the presence of cyclopentadiene. The expected cycloaddition was found to be reversible for the title compound, and transfer hydrogenation was the preferred pathway over long periods of time. Other tested substrates were able to undergo facile cycloaddition with considerable yields and without the parallel reduction. The work presented here defines the effect of Lewis acid catalysts on the reaction between cyclopentadiene and 3,3,6-trimethylcyclohex-5-ene-1,2,4-trione. Cycloaddition and hydrogenation reactions both occur in parallel. For cycloaddition, the dr was similar for all Lewis acids tested. Hydrogenation was catalyzed efficiently by AlCl3 and found to be the main mode of reaction for this particular system. Copyright

Access to dienophilic ene-triketone synthons by oxidation of diketones with an oxoammonium salt

Here we describe the oxidation of 1,3-cyclohexanediones with 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (Bobbitt's salt) to generate 5-ene-1,2,4-triones in moderate-to-good (40-80%) yields. This inexpensive oxidant facilitated an unprecedented cascade of oxidation and elimination to yield novel ene-triketones. The reactivity of these products was explored in the Diels-Alder reaction and provided moderate-to-good yields of cycloaddition products. The products described in this study represent unique, densely functionalized, and versatile building blocks for the synthesis of more complex molecules.