54343-55-4

Usage

Uses

Used in Organic Synthesis:
3-BENZOYL-1-METHYL-PYRROLIDIN-2-ONE is used as a reagent in organic synthesis for its ability to facilitate the formation of complex organic molecules, which are essential in the development of new pharmaceuticals and agrochemicals.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 3-BENZOYL-1-METHYL-PYRROLIDIN-2-ONE is used as a building block for the creation of various drugs. Its structural properties make it a key component in the synthesis of medicinal compounds.
Used in Agrochemical Production:
Similarly, in the agrochemical sector, 3-BENZOYL-1-METHYL-PYRROLIDIN-2-ONE is employed as a building block to develop compounds used in agriculture for pest control and crop protection.
Used in Heterocyclic Compound Synthesis:
3-BENZOYL-1-METHYL-PYRROLIDIN-2-ONE is used as a precursor in the synthesis of heterocyclic compounds, which are important in various chemical and pharmaceutical applications due to their unique properties and reactivity.
Used in Medicinal Chemistry Research:
3-BENZOYL-1-METHYL-PYRROLIDIN-2-ONE is utilized in medicinal chemistry research for its potential biological activity, making it a valuable tool for exploring new therapeutic agents and understanding molecular interactions.
Used in Polymer Material Production:
3-BENZOYL-1-METHYL-PYRROLIDIN-2-ONE is used as a key component in the production of certain polymer materials, contributing to the development of new materials with specific properties for various applications.
Used in Dye and Pigment Manufacturing:
In the manufacturing of dyes and pigments, 3-BENZOYL-1-METHYL-PYRROLIDIN-2-ONE is employed to produce colorants for a wide range of industrial uses, including textiles, plastics, and printing inks.

Upstream product

• 872-50-4 1-methyl-pyrrolidin-2-one 
• 98-88-4 benzoyl chloride 
• 93-89-0 benzoic acid ethyl ester 
• 16466-44-7 N-ethyl-N-phenylbenzamide 
• 19672-91-4 N-benzyl-N-phenylbenzamide 
• 93-98-1 N-phenyl benzoyl amide 
• 611-74-5 N,N-dimethylbenzamide 
• 74542-54-4 N,N-phenyl-p-toluenesulfonylbenzamide 
• 4051-56-3 N,N-diphenylbenzamide 
• 1934-92-5 N-methyl-N-phenyl-benzamide 
• 54343-54-3 Benzoic acid [1-methyl-2-oxo-pyrrolidin-(3E)-ylidene]-phenyl-methyl ester 

Downstream Products

• 116461-07-5 N-vinyl-3-oxo-3-phenyl propionic amide 
• 116461-09-7 1-methyl-3-phenacyl-2-pyrrolidone 
• 144587-26-8 7-methyl-2,4-diphenyl-5,6-dihydropyrrolo<2,3-d>pyrimidine 

Relevant academic research and scientific papers

Amides Activation: Transition Metal-Free Coupling Between C-N Activated Amides and Enolizable Amides

Transition metal-free Claisen-type condensation between two different amides was developed. N-phenyl-N-tosylbenzamide derivatives reacted with enolizable amides such as N-methyl pyrrolidinone and N,N-dimethyl acetamide in the presence of NaHMDS to give th

Nickel-Catalyzed Claisen Condensation Reaction between Two Different Amides

A nickel-catalyzed Claisen condensation reaction between two amides, where one possesses an α-proton, for the synthesis of β-ketoamides was developed. Ni(glyme)Cl2 and terpyridine serve as the active catalysts in the presence of Mn and LiCl. N,N-Methylphenyl and N,N-diphenyl benzamide derivatives react with cyclic and noncyclic amides to give their corresponding β-ketoamides in moderate to good yields. In addition, a DFT calculation suggests that reductive elimination is the rate-determining step.

A copper-mediated oxidative coupling route to 3H- and 1H-indoles from N-aryl-enamines

A facile copper(II)-mediated C-H bond oxidation and C-C bond formation procedure has been applied to the synthesis of indole derivatives. Intramolecular oxidative coupling of 3,3-disubstituted enamines proceeded using a non-expensive and air-stable copper

Manganese(III) acetate-mediated alkylation of β-keto esters and β-keto amides: An enantio- and diastereo-selective approach to substituted pyrrolidinones

β-Keto esters and β-keto amides can be efficiently alkylated on reaction with enol ethers and manganese(III) acetate in the presence of copper(II) acetate. These intermolecular radical addition reactions can be used to construct quaternary carbon centres in excellent yield and this method has been utilised in a diastereoselective approach to substituted pyrrolidinones.

Synthesis and the keto-enol equilibrium of 2-acyl lactams

Condensation of N-substituted lactams with carboxylic acid esters was studied. A wide range of substituted 2-acyl lactams with different ring sizes were synthesized. The structure of 2-acyl lactams (primarily, the ring size) was found to influence the ket

PHOTOCYCLISATION OF KETO-LACTAMS. A NEW SYNTHESIS OF FUNCTIONALIZED 1-AZA-BICYCLO(X.Y.0.)ALKANES

A series of 1-azabicyclo(x.y.0)alkanes has been synthesized using an intramolecular photoreduction.The methodology consists of a regioselective abstraction of a hydrogen α to the nitrogen of an amide by the triplet T1(n, ?*) of a carbonyl derivative.

Lactam Acetals: Part VIII - Further Investigation of Reactions with Araldehydes

o-Substituted araldehydes on reaction with 2,2-dimethoxy-1-methylpyrrolidine (1) first form dioxinopyrroles (2-6), which undergo facile hydrolysis to the (RR)-benzhydrols (7-11); the formation of 2-6 is particularly favoured with electron withdrawi