544-64-9 Usage
Description
Myristoleic Acid, a colorless liquid, is a naturally occurring monounsaturated fatty acid found in the fat of some seeds and fish oil. It possesses unique chemical properties that make it a promising compound for various applications, particularly in the medical field.
Uses
Used in Pharmaceutical Industry:
Myristoleic Acid is used as a therapeutic agent for the treatment of prostate cancer. It induces apoptosis and necrosis in human prostate cancer cell LNCaP, demonstrating its potential as a new tool in developing treatments for prostate cancer.
Used in Nutritional Supplements:
Myristoleic Acid, being a naturally occurring fatty acid, can be used as a component in nutritional supplements to support overall health and well-being. Its presence in fish oil and some seeds makes it a valuable addition to dietary supplements for those seeking a natural source of essential fatty acids.
Used in Research and Development:
Due to its unique chemical properties and potential applications in the medical field, Myristoleic Acid can be utilized in research and development for the discovery of new drugs and therapies. Its role in inducing apoptosis and necrosis in cancer cells makes it an interesting subject for further study and potential development of novel cancer treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 544-64-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 4 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 544-64:
(5*5)+(4*4)+(3*4)+(2*6)+(1*4)=69
69 % 10 = 9
So 544-64-9 is a valid CAS Registry Number.
InChI:InChI=1/C14H26O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14(15)16/h5-6H,2-4,7-13H2,1H3,(H,15,16)/b6-5-
544-64-9Relevant articles and documents
Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2
Mostyn, Shannon N.,Carland, Jane E.,Shimmon, Susan,Ryan, Renae M.,Rawling, Tristan,Vandenberg, Robert J.
, p. 1949 - 1959 (2017/09/26)
It has been demonstrated previously that the endogenous compound N-arachidonyl-glycine inhibits the glycine transporter GlyT2, stimulates glycinergic neurotransmission, and provides analgesia in animal models of neuropathic and inflammatory pain. However, it is a relatively weak inhibitor with an IC50 of 9 μM and is subject to oxidation via cyclooxygenase, limiting its therapeutic value. In this paper we describe the synthesis and testing of a novel series of monounsaturated C18 and C16 acyl-glycine molecules as inhibitors of the glycine transporter GlyT2. We demonstrate that they are up to 28 fold more potent that N-arachidonyl-glycine with no activity at the closely related GlyT1 transporter at concentrations up to 30 μM. This novel class of compounds show considerable promise as a first generation of GlyT2 transport inhibitors.
Substrate specificity of acetyltransferase and reductase enzyme systems used in pheromone biosynthesis by Asian corn borer, Ostrinia furnacalis
Zhao Cheng-Hua,Lu Fang,Bengtsson,Lofstedt
, p. 1495 - 1510 (2007/10/03)
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Pheromones, VII. Synthesis of 1 substituted (Z) 9 alkenes
Bestmann,Stransky,Vostrowsky,Range
, p. 3582 - 3595 (2007/10/05)
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