54458-44-5

Basic information

• Product Name: Benzenepropanoic acid, a-hydroxy-b-oxo-a-phenyl-, methyl ester
• CAS NO: 54458-44-5
• Molecular Formula: C16H14O4
• Molecular Weight: 270.285
• Mol File: 54458-44-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-hydroxy-b-oxo-a-phenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-hydroxy-b-oxo-a-phenyl-, methyl ester(54458-44-5)
• EPA Substance Registry System: Benzenepropanoic acid, a-hydroxy-b-oxo-a-phenyl-, methyl ester(54458-44-5)

Safety Data

• Hazardous Substances Data: 54458-44-5(Hazardous Substances Data)

Upstream product

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 98-88-4 benzoyl chloride 
• 1807-69-8 2-diazo-3-oxo-3-phenyl-propionic acid methyl ester 
• 86358-32-9 methyl 3-phenyl-2,3-dioxopropionate 
• 1078-58-6 diphenylzinc 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 367266-71-5 methyl 2,2-dihydroxy-3-oxo-3-phenylpropanoate 
• 94104-44-6 methyl 2,3-dibromo-2,3-diphenylpropanoate 
• 36854-27-0 2,3-diphenylacrylic acid methyl ester 
• 93-97-0 benzoic acid anhydride 

Downstream Products

• 54458-46-7 methyl 2,3-diphenyl-2-hydroxy-3-(hydroximino)propanoate 

Relevant articles and documents

Acylation of a transient Ti(IV)-enolate by acyl halides and anhydrides. Facile synthesis of α-hydroxy-β-ketoesters

Regioselective C-acylation at the carbonyl carbon of methyl phenylglyoxylate 1 occurs by reaction with a variety of acyl halides 3 and anhydrides 4 in the presence of TiCl3/py system in THF at room temperature. α-Hydroxy-β-ketoesters 5 are the

Efficient Synthesis of α-Hydroxy-β-ketoesters from Methyl Phenylglyoxalate and Acid Chlorides mediated by Titanium Trichloride

Methyl phenylglyoxalate and acid chlorides undergo rapid condensation reactions on treatment with a TiCl3-THF/CH2Cl2 solution, in the presence of pyridine, at room temperature.