54574-77-5

Upstream product

• 369363-26-8 diethyl 2-[dodecyl(p-methoxyphenyl)amino]malonate 
• 54723-13-6 2-(4-methoxyphenylimino)malonic acid diethyl ester 
• 124-22-1 n-Dodecylamine 
• 623-12-1 4-chloromethoxybenzene 
• 696-62-8 para-iodoanisole 
• 1120-16-7 lauric acid amide 
• 104-94-9 4-methoxy-aniline 
• 143-07-7 lauric acid 
• 15890-72-9 laurylmagnesium bromide 

Relevant academic research and scientific papers

Cobalt-Catalyzed Reductive Alkylation of Amines with Carboxylic Acids

Direct reductive alkylation of amines with carboxylic acid is carried out by using an inexpensive, air-stable cobalt/triphos catalytic system with molecular hydrogen as the reductant. This efficient synthetic method proceeds through reduction and condensation, followed by reduction of the in situ-generated imine into the amine in a green catalytic process.

Unexpected selectivity in ruthenium-catalyzed hydrosilylation of primary amides: Synthesis of secondary amines

Selective ruthenium-catalyzed reductive coupling of primary amides under hydrosilylation conditions is achieved using an one pot procedure. Using 3 equiv. of phenylsilane and [RuCl2(mesitylene)]2 (1-2 mol%) as the catalyst at 100 °C under neat conditions, secondary symmetric amines were obtained in good yields and with high chemoselectivities. The Royal Society of Chemistry 2013.

C-N bond formation catalysed by CuI Bonded to polyaniline nanofiber

Polyaniline nanofiber as a macroligand for the supported cuprous iodide catalyst (CuI-PANInf) has been developed for the coupling of aryl halides (including aryl chlorides) with aliphatic, aromatic, and N(H)-heterocyclic amines under ambient conditions (80 °C for aryl chlorides) has been developed. This simple and efficient method for coupling reactions is highly versatile, convenient, and also the catalyst can be used for several cycles with good-to-excellent yields.

Carbene adduct of cyclopalladated ferrocenylimine as an efficient catalyst for the amination of aryl chlorides

A novel air- and moisture-stable carbene adduct of cyclopalladated ferrocenylimine has been synthesized and characterized. The structure of this compound was determined by X-ray crystal structure analysis. This adduct has been applied as an efficient catalyst for the amination of aryl chlorides.

Iminomalonate as a convenient electrophilic amination reagent for grignard reagents

Diethyl 2-[N-(p-methoxyphenyl)imino]malonate underwent amination reactions with alkyl Grignard reagents to give N-aklylation products in good yields. The obtained N-alkylation products were readily converted into N-alkyl-panisidines by the oxidative removal of the malonate moiety. The p-methoxyphenyl group was subsequently deprotected to give primary amines.

Electrophilic amination with iminomalonate

Diethyl N-anisyliminomalonate has been found to be an excellent electrophilic amination reagent for Grignard reagents to give N-alkylated products in good yields, and subsequent air oxidation affords N-alkylanisidines.