5468-85-9

Basic information

• Product Name: N-phenyl-2-quinolinamine
• Synonyms: N-phenyl-2-quinolinamine;2-Anilinoquinoline
• CAS NO: 5468-85-9
• Molecular Formula: C₁₅H₁₂N₂
• Molecular Weight: 220.27
• Mol File: 5468-85-9.mol
• Article Data: 23

Chemical Properties

• Appearance: /
• Density: 1.15g/cm³
• Refractive Index: 1.571
• CAS DataBase Reference: N-phenyl-2-quinolinamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-2-quinolinamine(5468-85-9)
• EPA Substance Registry System: N-phenyl-2-quinolinamine(5468-85-9)

Safety Data

• Hazardous Substances Data: 5468-85-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C19H21N3O3/c1-14-7-6-10-17(11-14)25-13-19(24)20-12-18(23)22-21-15(2)16-8-4-3-5-9-16/h3-11H,12-13H2,1-2H3,(H,20,24)(H,22,23)/b21-15+

Upstream product

• 612-62-4 2-Chloroquinoline 
• 1865-45-8 sodium anilide 
• 62-53-3 aniline 
• 32888-95-2 (4-chloro-quinolin-2-yl)-phenyl-amine 
• 144752-25-0 Phenyl-(2-vinyl-phenyl)-carbodiimide 
• 109586-44-9 trifluoromethanesulfonic acid quinolin-2-yl ester 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 1436-43-7 quinoline-2-carbonitrile 
• 1613-37-2 Quinoline N-oxide 
• 622-16-2 1,3-Diphenylcarbodiimide 
• 622-34-4 1-phenylcyanamide 
• 2005-43-8 2-bromoquinoline 
• 703-61-7 2,4-dichloroquinoline 

Downstream Products

• 205-54-9 quinolino<1,2-a>benzimidazole 
• 1542248-04-3 1-acetyl-1-tert-butyl-3-phenyl-3-quinolin-2-yl-urea 
• 1283073-99-3 2-(2,3-diphenyl-1H-indol-1-yl)quinoline 
• 114414-78-7 neocryptolepine 
• 243-38-9 6H-quinindoline 
• 70611-37-9 2-Benzyl-1-oxo-4-phenyl-1H-pyrimido<1,2-a>chinolin-4-ium-3-olat 
• 85291-49-2 4-Benzyl-2-phenyl-2,3-dihydro-1H-pyrimido<3,4-a>chinolin-1,3-dion 
• 85291-53-8 2,4-Diphenyl-2,3-dihydro-1H-pyrimido<3,4-a>chinolin-1,3-dion 
• 85291-57-2 4,4,4a-Trichlor-2-phenyl-2,3,4,4a-tetrahydro-1H-pyrimido<3,4-a>chinolin-1,3-dion 
• 85291-48-1 3-Benzyl-1-(2-chinolinyl)-4-hydroxy-chinolin-2(1H)-on 
• 85291-56-1 2-Phenyl-2,3-dihydro-1H-pyrimido<3,4-a>chinolin-1,3-dion 

Relevant articles and documents

Cyano-Sacrificial (Arylthio)arylamination of Quinoline and Isoquinoline N-Oxides Using N-(2-(Arylthio)aryl)cyanamides

A copper(I)-catalyzed regioselective arylthio-arylamination of quinoline and isoquinoline N-oxides has been achieved at the expense of a cyano (CN) group from N-(2-(arylthio)aryl)cyanamides. This reductive amination proceeds in one pot at 80 °C in the absence of any additives. This is a unique demonstration of aryl cyanamides serving as arylaminating agents on quinoline/isoquinoline N-oxides with concurrent autoreduction of N-oxide.

Nickel-Catalyzed Amination of Aryl Nitriles for Accessing Diarylamines through C?CN Bond Activation

A nickel-catalyzed amination to access diarylamines has been developed through C?CN bond activation of aryl nitriles with anilines. In this developed catalytic protocol, various aromatic and heteroaromatic nitriles could be utilized as the electrophiles to couple with substituted anilines. A diversity of diarylamines were obtained in 15–95% yields. (Figure presented.).

A mild and metal-free synthesis of 2- And 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines

A simple synthetic strategy has been developed for the synthesis of 2- and 1-alkyl/aryl/dialkylaminoquinolines and isoquinolines from the easily available quinoline and isoquinoline-N-oxides, different amines, triflic anhydride as activating agent and ace