54743-42-9

Basic information

• Product Name: 1-Propanone, 3-(1,3-dioxolan-2-yl)-1-phenyl-
• Synonyms: 4-oxo-4-phenylbutanal ethylenacetal;3-[1,3]Dioxolan-2-yl-1-phenyl-propan-1-one
• CAS NO: 54743-42-9
• Molecular Formula: C12H14O3
• Molecular Weight: 206.241
• Mol File: 54743-42-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 3-(1,3-dioxolan-2-yl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 3-(1,3-dioxolan-2-yl)-1-phenyl-(54743-42-9)
• EPA Substance Registry System: 1-Propanone, 3-(1,3-dioxolan-2-yl)-1-phenyl-(54743-42-9)

Safety Data

• Hazardous Substances Data: 54743-42-9(Hazardous Substances Data)

Usage

General Description

1-Propanone, 3-(1,3-dioxolan-2-yl)-1-phenyl- is a chemical compound with the molecular formula C12H14O2. It is also known as dihydroxyacetone phenylhydrazone and is widely used in organic synthesis and as a reagent in biochemical research. 1-Propanone, 3-(1,3-dioxolan-2-yl)-1-phenyl- is a ketone with a phenyl group and a dioxolane ring attached to the carbonyl carbon. It is commonly used as a reagent in the synthesis of pharmaceuticals and agrochemicals, and it also exhibits antibacterial and antifungal properties. Additionally, 1-Propanone, 3-(1,3-dioxolan-2-yl)-1-phenyl- has been studied for its potential applications in the treatment of neurological disorders and as a building block for the development of new drugs.

Upstream product

• 37610-80-3 1,3-dioxolan-2-ylethylmagnesium bromide 
• 98-88-4 benzoyl chloride 
• 646-06-0 1,3-DIOXOLANE 
• 768-03-6 Phenyl vinyl ketone 
• 118817-79-1 3-[1,3]-dioxolan-2-ylthiopropionic acid S-phenyl ester 

Downstream Products

• 98-86-2 acetophenone 
• 56139-59-4 4-oxo-4-phenyl-butyraldehyde 

Relevant articles and documents

Photochemical Synthesis of 4-Oxobutanal Acetals and of 2-Hydroxycyclobutanone Ketals

Irradiation of α,β-unsaturated ketones (aliphatic, both open chain and cyclic as well as aryl substituted) in 1,3-dioxolane in the presence of a sensitizer (benzophenone or anthraquinone) led to 4-oxobutanal acetals in fair to excellent yield through a very simple procedure (workup in most cases by bulb-to-bulb distillation). The resulting acetals were irradiated to give 2-hydroxycyclobutanone ketals, again through a simple procedure that gave a good yield with open-chain aliphatic derivatives.

A NEW READY ROUTE TO 1,4-KETOALDEHYDES AND 1,4-DIKETONES WITH APPLICATION TO THE SYNTHESIS OF Z-JASMONE AND DIHYDROJASMONE

A new three-step synthesis in good overall yield of 1,4-ketoaldehydes and 1,4-diketones is described.The method involves two sequential coupling reaction of reagents with S-phenyl carbonochloridothioate in the presence of nickel(II) or iron(III) complexes as catalysts.Application of this reaction to the synthesis of Z-jasmone and dihydrojasmone is also described.