54755-95-2

Upstream product

• 60-29-7 diethyl ether 
• 62-53-3 aniline 
• 1638-63-7 2-acetoxy-2-phenylacetyl chloride 
• 54755-88-3 S-(p-Tolyl)-2-acetoxy-2-phenylthioacetat 
• 4410-33-7 N-phenyl-2-hydroxy-4-phenylacetamide 
• 108-24-7 acetic anhydride 
• 41103-87-1 1-phenyl-2-(p-tolylsulfinyl)ethan-1-ol 
• 75-36-5 acetyl chloride 
• 611-73-4 Benzoylformic acid 
• 25726-04-9 phenylglyoxylyl chloride 
• 17530-89-1 p-tolyl phenacyl sulphoxide 
• 3543-98-4 1,3-diphenyl-2,2-dichloroaziridine 
• 463-51-4 Ketene 
• 611-71-2 MANDELIC ACID 

Relevant academic research and scientific papers

Potassium Phosphate-Catalyzed Chemoselective Reduction of α-Keto Amides: Route to Synthesize Passerini Adducts and 3-Phenyloxindoles

A chemoselective reduction of α-keto amides to biologically important α-hydroxy amides (mandelamides) by polymethylhydrosiloxane (PMHS) using 5 mol% potassium phosphate (K3PO4) as catalyst has been developed. This transition metal-free protocol discloses excellent chemoselectivity for the ketone reduction of α-keto amides in the presence of other reducible functionalities like ketone, nitro, halides, nitrile and amide. Also, the chemoselectively reduced α-hydroxy amide has been derivatized to isocyanide-free Passerini adducts. The N-alkyl-α-hydroxy amides have been successfully converted to 3-phenyloxindole derivatives by treatment with methanesulfonyl cholride and triethylamine.

The Chemistry of 5-Oxodihydroisoxales. XI; The Photolysis of 3-Hydroxy-4-phenylisoxazol-5(2H)-ones (Phenyldisic Acids)

3-Hydroxy-2-methyl-4-phenylisoxazol-5(2H)-one, 3-hydroxy-2,4-diphenylisoxazol-5(2H)-one and phenyldisic acid have been photolysed at 254 nm in hydroxylic solvents.By comparision of the respective products with those obtained from 3-methoxy-4-phenylisoxazo

1,3-DIARYL-2,2-DIHALOAZIRIDINES IN NITRATION AND BROMINATION REACTIONS

In the nitration of 3-(4-nitrophenyl)-1-phenyl-2,2-dichloroaziridine in acetic acid, 1-(o- and p-nitrophenyl)-derivatives are formed in a 35:65 ratio. 1,3-Diphenyl-2,2-dichloroaziridine undergoes opening of the three-membered ring under the same conditions, forming a mixture of o- and p-nitroanilides and 2-nitro-4-chloroanilides of 2-acetoxy (or 2-chloro)-2-phenylacetic acids.The bromination of 3-(4-nitrophenyl)-1-phenyl-2,2-dichloroaziridine in aqueous acetic acid leads to 1-(4-bromophenyl)-3-(4-nitrophenyl)-2,2-dichloroaziridine, while in a mixture of acetic acid and acetic anhydride it leads to the anilide of 2-bromo-2-phenylacetic acid and 2-bromo-N-(2,4-dibromophenyl)-1-(4-nitrophenyl)-2,2-dichloroethylamine.