54826-37-8Relevant academic research and scientific papers
Dioxoiodane Compounds as Versatile Sources for Iodine(I) Chemistry
Mu?iz, Kilian,García, Belén,Martínez, Claudio,Piccinelli, Alessandro
, p. 1539 - 1545 (2017)
The general synthesis, isolation and characterization of electrophilic iodine reagents of the general formula R4N[I(O2CAr)2] is reported. These compounds are air- and moisture-stable iodine(I) reagents, which were characterized including X-ray analysis. They represent conceptually new iodine(I) reagents with anions as stabilizers. These compounds display the expected performance as electrophilic reagents upon interaction with electron-rich substrates. The performance of these compounds in a total of 47 different reactions of vicinal iodooxygenation of alkenes is studied and some key features on the reagents are revealed.
Regioselective vicinal functionalization of unactivated alkenes with sulfonium iodate(i) reagents under metal-free conditions
Rao, Dodla S.,Reddy, Thurpu R.,Babachary, Kalvacherla,Kashyap, Sudhir
, p. 7529 - 7543 (2016/08/16)
Metal-free, molecular iodine-free direct 1,2-difunctionalization of unactivated alkenes has been reported. The sulfonium iodate(i) reagent efficiently promoted the intermolecular vicinal iodo-functionalization of a diverse range of olefins in a stereo and regioselective manner. This method enables the divergent and straightforward preparation of synthetically useful functionalities; β-iodocarboxylates, β-iodohydrins, and β-iodoethers in a one-step process. Further interconversion of iodo-functionalized derivatives allows easy access to valuable synthetic intermediates en route to biologically active molecules.
N-iodosuccinimide: A highly effective regioselective reagent for iodoesterification of alkenes
Reddy, Aleti R.,Sangwan, Payare L.,Chinthakindi, Praveen K.,Farooq, Saleem,Siddaiah, Vidavalur,Koul, Surrinder
, p. 1313 - 1324 (2013/08/23)
A rapid, convenient, and efficient method has been achieved for regioselective iodoesterification of alkenes with aliphatic and aromatic acids, and protected amino acids in the presence of N-iodosuccinimide (NIS) in nearly quantitative yields. Optically enriched iodohydrins have been achieved by LiAlH4 (LAH) reduction of diastereoisomeric iodo esters. Copyright
